Evidence map›Paper›PMID 34930022›Full record

ArticleThe British journal of radiology2022

Shortening the preparation time of the single prolonged breath-hold for radiotherapy sessions.

Michael John Parkes, Stuart Green, Jason Cashmore, Qamar Ghafoor, Thomas Clutton-Brock

Abstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael John ParkesSchool of Sport, Exercise & Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Stuart GreenHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Jason CashmoreHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Qamar GhafoorHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Thomas Clutton-BrockNational Institute for Health Research (NIHR)/Wellcome Trust Birmingham Clinical Research Facility, Birmingham, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveSingle prolonged breath-holds of >5 min can be obtained in cancer patients. Currently, however, the preparation time in each radiotherapy session is a practical limitation for clinical adoption of this new technique. Here, we show by how much our original preparation time can be shortened without unduly compromising breath-hold duration.

methods44 healthy subjects performed single prolonged breath-holds from 60% O

resultsMean original breath-hold duration was 6.5 ± 0.2 (standard error) min. The total original preparation time (from connecting the facemask to the start of the breath-hold) was 26 ± 1 min. After shortening the hypocapnia duration from 16 to 5 min, mean breath-hold duration was still 6.1 ± 0.2 min (

conclusionsThese improvements may facilitate adoption of the single prolonged breath-hold for a range of thoracic and abdominal radiotherapies especially involving hypofractionation. ADVANCES IN KNOWLEDGE: Multiple short breath-holds improve radiotherapy for thoracic and abdominal cancers. Further improvement may occur by adopting the single prolonged breath-hold of >5 min. One limitation to clinical adoption is its long preparation time. We show here how to reduce the mean preparation time from 26 to 3.5 min without compromising breath-hold duration.

Indexed as

Adaptation, PhysiologicalBreath HoldingHyperventilationHypocapniaAbdominal NeoplasmsAdultDose Fractionation, RadiationFemaleHealthy VolunteersHumansMaleMasksRadiotherapyThoracic NeoplasmsTime FactorsYoung Adult

Identifiers

PMID34930022
PMCPMC8822572

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.