Evidence map›Paper›PMID 34929372›Full record

ArticleThe journal of allergy and clinical immunology. In practice2022

Low IgG trough and lymphocyte subset counts are associated with hospitalization for COVID-19 in patients with primary antibody deficiency.

John K Kuster, Serhan Unlu, Thomas A Makin, Jennefer Par-Young, Michael Simonov, Shamsa Shafi, Matthew Balanda, Christopher Randolph, Ryan Steele, Florence Ida Hsu and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Severity of SARS-CoV-2 infection in children with inborn errors of immunity (primary immunodeficiencies): a systematic review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
  3. Safety and tolerability of Evusheld in patients with CVID: The Mayo Clinic experience.The journal of allergy and clinical immunology. Global · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. COVID-19 and Inborn Errors of Immunity.Physiology (Bethesda, Md.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

John K KusterSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Serhan UnluSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Thomas A MakinDivision of Asthma, Allergy, & Immunology, Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Va.
Jennefer Par-YoungSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Michael SimonovClinical and Translational Research Accelerator (CTRA), Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Shamsa ShafiSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Matthew BalandaThe Center for Allergy, Asthma, & Immunology, Waterbury, Conn.
Christopher RandolphThe Center for Allergy, Asthma, & Immunology, Waterbury, Conn.
Ryan SteeleSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Florence Ida HsuSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Christina PriceSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Anita Kohli-PamnaniAllergy, Asthma & Immunology Center, LLC, Milford, Conn.
Larry BorishDivision of Asthma, Allergy, & Immunology, Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Va.
Monica G LawrenceDivision of Asthma, Allergy, & Immunology, Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Va.
Insoo KangSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Junghee J ShinSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn. Electronic address: junghee.shin@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Primary Immunodeficiency DiseasesHospitalizationHumansImmunoglobulin GLymphocyte CountLymphocyte SubsetsSARS-CoV-2Immunoglobulin G

Identifiers

PMID34929372
PMCPMC8683251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.