Evidence map›Paper›PMID 34929108›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Associations of Monocyte Count and Other Immune Cell Types with Interstitial Lung Abnormalities.

John S Kim, Gísli Thor Axelsson, Matthew Moll, Michaela R Anderson, Elana J Bernstein, Rachel K Putman, Tomoyuki Hida, Hiroto Hatabu, Eric A Hoffman, Ganesh Raghu and 15 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05716022 (Hiatal Hernia and Pulmonary Involvement Related to Subclinical Lung Injury and Fibrosis), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05716022 completednot on this mapstarted 2023, after this paper: background citation

Hiatal Hernia and Pulmonary Involvement Related to Subclinical Lung Injury and Fibrosis

TypeobservationalSponsorUniversity of VirginiaRan2023 to 2025Enrolled14ConditionsHiatal Hernia, Interstitial Lung DiseaseArmsBlood Collection, Bronchoscopy
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Peripheral blood monocyte count and outcomes in patients with interstitial lung disease: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Genomic and Serological Rheumatoid Arthritis Biomarkers,Annals of the American Thoracic Society · 2025
    Article
  15. Review
  16. Article
  17. Approach to Clinical Trials for the Prevention of Pulmonary Fibrosis.Annals of the American Thoracic Society · 2023
    Article
  18. Article
  19. Cigarette Smoking, and Blood Monocyte Count Correlate with Chronic Lung Injuries and Mortality.International journal of chronic obstructive pulmonary disease · 2023
    Article
  20. Article
4 · The record

Corrections and comments

  • Commented on by
    2022
5 · Who and what money

Authors and funding

25 authors at 13 institutions in 3 countries.

John S KimDepartment of Medicine, and.
Gísli Thor AxelssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Matthew MollDivision of Pulmonary and Critical Care and.
Michaela R AndersonDepartment of Medicine, Columbia University, New York, New York.
Elana J BernsteinDepartment of Medicine, Columbia University, New York, New York.
Rachel K PutmanDivision of Pulmonary and Critical Care and.
Tomoyuki HidaDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Hiroto HatabuDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Eric A HoffmanDepartment of Radiology.
Ganesh RaghuDepartment of Medicine, University of Washington, Seattle, Washington.
Steven M KawutDepartment of Medicine and.
Margaret F DoyleDepartment of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Colchester, Vermont.
Russell TracyDepartment of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Colchester, Vermont.
Lenore J LaunerLaboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute of on Aging, National Institutes of Health, Bethesda, Maryland.
Ani ManichaikulCenter for Public Health Genomics and Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia.
Stephen S RichCenter for Public Health Genomics and Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia.
David J LedererRegeneron Pharmaceuticals, Inc., Tarrytown, New York.
Vilmundur GudnasonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Brian D HobbsDivision of Pulmonary and Critical Care and.
Michael H ChoDivision of Pulmonary and Critical Care and.
Gary M HunninghakeDivision of Pulmonary and Critical Care and.
Christine Kim GarciaDepartment of Medicine, Columbia University, New York, New York.
Gunnar GudmundssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
R Graham BarrDepartment of Medicine, Columbia University, New York, New York.
Anna J PodolanczukDepartment of Medicine, Columbia University, New York, New York.
Brigham and Women's Hospital · USColumbia University · USPulmonary and Critical Care Associates · USUniversity of Iceland · ISUniversity of Vermont · USVirginia Department of Health · USCornell University · USNational Institutes of Health · USRegeneron (United States) · USReykjavík University · ISUniversity of Iowa · USUniversity of Pennsylvania · USUniversity of Washington · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Pulmonary microvascular perfusion in the Multi-Ethnic Study of AtherosclerosisR01HL077612 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2004 to 2026
$18.8M
Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary Disease (COPD)R01HL093081 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2008 to 2026
$17.2M
SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASEST32HL007427 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI DAWN L DEMEO, Edwin K Silverman · 1985 to 2026
$13.6M
Clinical Genetics and Screening for Pulmonary FibrosisR01HL130974 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GARY MATTHEW HUNNINGHAKE, Benjamin Alexander Raby · 2016 to 2026
$10.0M
Genetic and Genomic Characterization of the Occurrence and Progression of Interstitial Lung AbnormalitiesR01HL135142 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL H. CHO, GARY MATTHEW HUNNINGHAKE · 2017 to 2026
$7.7M
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1-TR-000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1-TR-001079NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1-TR-001420NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS HSN268201500003INHLBI NIH HHS K08 HL136928NHLBI NIH HHS K08-HL136928NHLBI NIH HHS K08 HL140087NHLBI NIH HHS K23-HL-140087NHLBI NIH HHS K23 HL140199NHLBI NIH HHS K23-HL-140199NHLBI NIH HHS K23-HL-1502080NHLBI NIH HHS K23 HL150301NHLBI NIH HHS K23-HL-150301NHLBI NIH HHS K24 HL103844NHLBI NIH HHS K24-HL-103844NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS N01-HC-95159NHLBI NIH HHS N01-HC-95160NHLBI NIH HHS N01-HC-95161NHLBI NIH HHS N01-HC-95162NHLBI NIH HHS N01-HC-95163NHLBI NIH HHS N01-HC-95164NHLBI NIH HHS N01-HC-95165NHLBI NIH HHS N01-HC-95166NHLBI NIH HHS N01-HC-95167NHLBI NIH HHS N01-HC-95168NHLBI NIH HHS N01-HC-95169NHLBI NIH HHS R01 HL077612NHLBI NIH HHS R01-HL077612NHLBI NIH HHS R01 HL093081NHLBI NIH HHS R01-HL093081NHLBI NIH HHS R01 HL103676NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01-HL111024NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01-HL130974NHLBI NIH HHS R01 HL135142NHLBI NIH HHS R01-HL135142NHLBI NIH HHS R01 HL137927NHLBI NIH HHS R01-HL137927NHLBI NIH HHS RC1 HL100543NHLBI NIH HHS RC1-HL100543NHLBI NIH HHS T32 HL007427NHLBI NIH HHS T32-HL007427NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01-HL089856NHLBI NIH HHS U01 HL089897NHLBI NIH HHS U01-HL089897NIAMS NIH HHS K23 AR075112NIAMS NIH HHS K23-AR-075112NIA NIH HHS HHSN27120120022CNIA NIH HHS N01-AG-1-2100NIDDK NIH HHS P30 DK054759NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung Diseases, InterstitialRespiratory System AbnormalitiesAdultHumansLungMonocytesTomography, X-Ray Computedimmunityinterstitial lung abnormalitiesmonocyte

Identifiers

PMID34929108
PMCPMC10394677
OpenAlexW4200083368

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.