Evidence map›Paper›PMID 34928719›Full record

Trial reportAnnals of the Royal College of Surgeons of England2022

Patient characteristics and refusal to participate in a head and neck cancer intervention trial: experience of two tertiary UK head and neck cancer centres.

S N Rogers, D Lowe, V Highet, G Dukanovic, C Lowies, S Thomas, A Kanatas

Open access · greenAbstract readRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Annals of the Royal College of Surgeons of England, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

S N RogersFaculty of Health and Social Care, Edge Hill University, Ormskirk, UK.
D LoweAstraglobe Ltd, Congleton, Cheshire.
V HighetLiverpool Head and Neck Centre, Liverpool University Hospital Aintree, Liverpool, UK.
G DukanovicDental Translational Clinical Research Unit, Leeds Dental Institute, University of Leeds, UK.
C LowiesLiverpool Head and Neck Clinical Trials, Clinical Sciences Building, University Hospital Aintree, Liverpool, UK.
S ThomasUniversity of Bristol, University Hospital Bristol and Weston NHS Trust, Bristol, UK.
A KanatasLeeds Teaching Hospitals and St James Institute of Oncology, Leeds Dental Institute and Leeds General Infirmary, Leeds, UK.
Edge Hill University · GBLeeds General Infirmary · GBRoyal Liverpool University Hospital · GBUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of Leeds · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRandomised clinical trials are an essential component for robust clinical evaluation. They are expensive to deliver but can fail to achieve the required outcomes. This paper reports details of trial recruitment in a head and neck Patient Concerns Inventory intervention trial from two UK head and neck tertiary centres. MATERIALS AND

methodsData were collected for a pragmatic cluster preference randomised control trial with 15 consultants recruiting patients treated with curative intent after a diagnosis of head and neck cancer (all sites, disease stages, treatments). Ethical approval was given to report on those not recruited by the following characteristics: trial site, trial arm, age, sex, tumour site, overall stage, index of multiple deprivation quintile, timeframe.

resultsThere were 368 patients approached who remained eligible and 80 (22%) declined to participate. Logistic regression suggested that age group (

conclusionsAlthough recruitment to the trial was very good, it raised the issue of lower recruitment in the more deprived older group and lower social economic strata. Innovative ways need to be explored to facilitate the 'hard to reach' group contributing to, and benefiting from, clinical trials.

Indexed as

Head and Neck NeoplasmsRefusal to ParticipateHumansQuality of LifeUnited KingdomHead and neck cancer recruitmentHealth-related quality of lifeInterventionPatient concerns inventoryPrompt listRandomised clinical trial

Identifiers

PMID34928719
PMCPMC10335026
OpenAlexW4200374835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.