Evidence map›Paper›PMID 34928439›Full record

ArticleInsights into imaging2021

Economic impact of spectral body imaging in diagnosis of patients suspected for occult cancer.

Michael Brun Andersen, Dyveke Ebbesen, Jesper Thygesen, Matthijs Kruis, Qing Gu, Ekta Dharaiya, Finn Rasmussen

Abstract read
In one paragraph

Article in Insights into imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael Brun AndersenDepartment of Radiology, Copenhagen University Hospital, Gentofte Hospitalsvej 1, 2900, Hellerup, Denmark. Michael.brun.andersen@regionh.dk.ORCID http://orcid.org/0000-0003-4886-5620
Dyveke EbbesenDepartment of Radiology, Aarhus University Hospital, Skejby, Denmark.
Jesper ThygesenCentral Denmark Region, Department of Clinical Engineering, Aarhus University Hospital, Skejby, Denmark.
Matthijs KruisPhilips Healthcare, Best, The Netherlands.
Qing GuPhilips Healthcare, Cleveland, USA.
Ekta DharaiyaPhilips Healthcare, Cleveland, USA.
Finn RasmussenDepartment of Radiology, Aarhus University Hospital, Skejby, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBased on prior studies spectral CT has shown a higher sensitivity for malignant lesions than conventional CT at the cost of lower specificity. For the radiologists, it also offers a higher degree of certainty in the diagnosis of benign lesions. The objective of this study was to evaluate the economic impact of spectral CT in patients suspected of occult cancer in a medical center in Denmark.

methodsThis study was a secondary analysis using de-identified data from a prospective study of patients receiving a contrast-enhanced spectral CT scan. Based on suggested follow-up examinations on both spectral CT and contrast-enhanced CT, costs from a payer's perspective were determined using unit costs obtained from national databases.

resultsThe dataset contained 400 patients. Overall, 203 follow-up procedures were eliminated based on spectral data reading. The largest reduction in suggested follow-up procedures was found for the kidney (83%), followed by the liver (66%), adrenal glands (60%), and pancreas (42%). The total estimated costs for suggested follow-up procedures based on spectral data reading were €155,219, 25.2% (€52,384) less than that of conventional CT reading.

conclusionOur results provide support for spectral body imaging as an advanced imaging modality for suspected occult cancer. A substantial number of follow-up diagnostic procedures could be eliminated based on spectral data reading, which would result in significant cost savings.

Indexed as

Contrast enhanced CTHealthcare economicsSpectral CT

Identifiers

PMID34928439
PMCPMC8688640

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.