Evidence map›Paper›PMID 34928168›Full record

ArticleThe British journal of radiology2022

Acute haemorrhage rate in 28,000 Out-of-Hours CT heads.

Katherine C Hocking, Catriona R Wright, Utku Alhun, Frances Hughes, Vartan J Balian, Mohammed A K Kabuli, George Tse, Maria McGonnell, Annu Chopra, Nikhil Kotnis and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Katherine C HockingSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Catriona R WrightSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Utku AlhunSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Frances HughesSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Vartan J BalianSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Mohammed A K KabuliSalford Royal NHS Foundation Trust, Salford, UK.
George TseSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Maria McGonnellSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Annu ChopraSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Nikhil KotnisSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Daniel ConnellySheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Samer AlabedSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Sheffield Teaching Hospitals NHS Foundation Trust · GBSalford Royal NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this paper is to assess the acute haemorrhage rate in patients who had CT head investigation out-of-hours with and without trauma and compare the rates of haemorrhage between warfarin and DOACs, at a busy teritary teaching hospital.

methodsAll CT heads performed between January 2008 and December 2019 were identified from the radiology information system (RIS) at Sheffield Teaching Hospitals (STH), with the requesting information being available from January 2015. The clinical information was assessed for the mention of trauma or anticoagulation, and the reports were categorised into acute and non-acute findings.

resultsBetween 2008 and 2019 the number of scans increased by 63%, with scans performed out of hours increasing by 278%. Between 2015 and 2019, the incidence of acute ICH was similar over the 5-year period, averaging at 6.9% and ranging from 6.1 to 7.6%. The rate of detection of acute haemorrhage following trauma was greater in those not anticoagulated (6.8%), compared with patients on anticoagulants such as warfarin (5.2%) or DOACs (2.8%).

conclusionsOver 12 years, there has been a significant increase in the number of CT heads performed at STH. The rate of ICH has remained steady over the last 5 years indicating a justified increase in imaging demand. However, the incidence of ICH in patients prescribed DOACs is lower than the general population and those on warfarin. ADVANCES IN KNOWLEDGE: This finding in a large centre should prompt discussion of the risk of bleeding with DOACs in relation to CT head imaging guidelines.

Indexed as

AdolescentAdultAfter-Hours CareAgedAged, 80 and overAnticoagulantsCraniocerebral TraumaFactor Xa InhibitorsFemaleHumansIntracranial HemorrhagesMaleMiddle AgedTomography, X-Ray ComputedTrauma CentersUnited KingdomAnticoagulantsFactor Xa InhibitorsWarfarin

Identifiers

PMID34928168
PMCPMC8822576
OpenAlexW4200173702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.