Evidence map›Paper›PMID 34928109›Full record

ArticlePediatric endocrinology, diabetes, and metabolism2021

To increase body height and muscle strength - one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy.

Joanna A Chrzanowska, Lidia Bubula, Anna Noczyńska, Agnieszka Zubkiewicz-Kucharska

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric endocrinology, diabetes, and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joanna A ChrzanowskaDepartment of Endocrinology and Diabetology of the Developmental Age, Medical University of Wroclaw, Poland.
Lidia BubulaStudent Scientific Club at the Department of Endocrinology and Diabetology of the Developmental Age, Medical University of Wroclaw, Poland.
Anna NoczyńskaDepartment of Endocrinology and Diabetology of the Developmental Age, Medical University of Wroclaw, Poland.
Agnieszka Zubkiewicz-KucharskaDepartment of Endocrinology and Diabetology of the Developmental Age, Medical University of Wroclaw, Poland.
University of Wrocław · PLWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coexistence of 2 genetic diseases can mutually modify their course. We describe the case of a 10-year-old boy with Sliver-Russell syndrome (SRS) and Duchenne muscular dystrophy (DMD). The patient's short stature, which is part of the clinical picture of both diseases, has been additionally aggravated by the steroid therapy, which is necessary to delay the progression of DMD. From the age of 9 years, the patient was treated with recombinant human growth hormone (rhGH) for 18 months. The following study discusses whether rhGH therapy in a child with SRS and DMD may alleviate or worsen the course of DMD, and how it affects carbohydrate metabolism disorders.

Indexed as

Muscular Dystrophy, DuchenneSilver-Russell SyndromeBody HeightChildGlucocorticoidsHumansMaleMuscle StrengthGlucocorticoidsDuchenne muscular dystrophygrowth hormoneSilver-Russell syndrome.

Identifiers

PMID34928109
PMCPMC10226341
OpenAlexW4200113898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.