Evidence map›Paper›PMID 34927457›Full record

ArticleThyroid : official journal of the American Thyroid Association2022

Mechanisms in Graves Eye Disease: Apoptosis as the End Point of Insulin-Like Growth Factor 1 Receptor Inhibition.

Syed A Morshed, Risheng Ma, Rauf Latif, Terry F Davies

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  9. Article
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  11. TSH enhances neurite outgrowth.Frontiers in endocrinology · 2024
    Article
  12. Article
  13. Review
  14. The Adverse Effects Profile of Teprotumumab.The Journal of clinical endocrinology and metabolism · 2023
    Review
  15. Review
  16. Understanding Pathogenesis Intersects With Effective Treatment for Thyroid Eye Disease.The Journal of clinical endocrinology and metabolism · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Syed A MorshedThyroid Research Unit, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Risheng MaThyroid Research Unit, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Rauf LatifThyroid Research Unit, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-4226-3728
Terry F DaviesThyroid Research Unit, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0003-3909-2750
Mount Sinai Hospital · US

Funding

TSH RECEPTOR MULTIMERIZATIONI01BX000800 · VA · JAMES J PETERS VA MEDICAL CENTER · PI DAVIES, TERRY FRANCIS · 2011 to 2025
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BLRD VA I01 BX000800
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Graves DiseaseGraves OphthalmopathyAnimalsAntibodies, MonoclonalApoptosisDiplopiaFibroblastsHumansImmunoglobulins, Thyroid-StimulatingInflammationInsulin-Like Growth Factor IMiceProteomicsReceptor, IGF Type 1Receptors, ThyrotropinThyrotropinAntibodies, MonoclonalImmunoglobulins, Thyroid-StimulatingInsulin-Like Growth Factor IReceptor, IGF Type 1Receptors, ThyrotropinThyrotropinGraves' orbitopathyIGF-1RteprotumumabTSHR antibody

Identifiers

PMID34927457
PMCPMC9048181
OpenAlexW4200351585

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.