ArticleBone & joint research2021
Cortical bone thickness of the distal radius predicts the local bone mineral density.
Article in Bone & joint research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Cortical indices, DXA, and FRAX as indicators of bone fragility: a comparative human cadaveric study.JBMR plus · 2026Article
- Insights into predicting residual plate bending in vivo using sensor-informed finite element models.Journal of orthopaedic translation · 2026Article
- Author's reply to the letters regarding "Preclinical validation of finite element models for predicting in vivo residual plate bending using continuous implant sensor data".Journal of orthopaedic translation · 2026Article
- Lower average cortical bone thickness predicts cemented fixation in short-stem reverse shoulder arthroplasty.Journal of orthopaedic surgery and research · 2026Article
- Quantitative Computed Tomography-Based Analysis of Bone Structure in the Surgical Neck of the Humerus during Aging in Men.Calcified tissue international · 2025Article
- Incidence and predictors of dorsal comminution in older adults with low-energy distal radius fracture.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Article
- Bone quality in total shoulder arthroplasty: a prospective study correlating computed tomography Hounsfield units with thumb test and fracture risk assessment tool score.JSES international · 2023Article
- The medial cortical ratio as a risk factor for failure after surgical fixation of proximal humerus fractures in elderly patients.Joint diseases and related surgery · 2023Article
- Associations Among Hip Structure, Bone Mineral Density, and Strength Vary With External Bone Size in White Women.JBMR plus · 2023Article
- Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density.Bone & joint research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe distal radius is a major site of osteoporotic bone loss resulting in a high risk of fragility fracture. This study evaluated the capability of a cortical index (CI) at the distal radius to predict the local bone mineral density (BMD).
methodsA total of 54 human cadaver forearms (ten singles, 22 pairs) (19 to 90 years) were systematically assessed by clinical radiograph (XR), dual-energy X-ray absorptiometry (DXA), CT, as well as high-resolution peripheral quantitative CT (HR-pQCT). Cortical bone thickness (CBT) of the distal radius was measured on XR and CT scans, and two cortical indices mean average (CBTavg) and gauge (CBTg) were determined. These cortical indices were compared to the BMD of the distal radius determined by DXA (areal BMD (aBMD)) and HR-pQCT (volumetric BMD (vBMD)). Pearson correlation coefficient (r) and intraclass correlation coefficient (ICC) were used to compare the results and degree of reliability.
resultsThe CBT could accurately be determined on XRs and highly correlated to those determined on CT scans (r = 0.87 to 0.93). The CBTavg index of the XRs significantly correlated with the BMD measured by DXA (r = 0.78) and HR-pQCT (r = 0.63), as did the CBTg index with the DXA (r = 0.55) and HR-pQCT (r = 0.64) (all p < 0.001). A high correlation of the BMD and CBT was observed between paired specimens (r = 0.79 to 0.96). The intra- and inter-rater reliability was excellent (ICC 0.79 to 0.92).
conclusionThe cortical index (CBTavg) at the distal radius shows a close correlation to the local BMD. It thus can serve as an initial screening tool to estimate the local bone quality if quantitative BMD measurements are unavailable, and enhance decision-making in acute settings on fracture management or further osteoporosis screening. Cite this article:
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.