ArticleJournal of clinical and translational pathology2021
Liver Involvement by Perforated Peptic Ulcer: A Systematic Review.
Article in Journal of clinical and translational pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
objectiveLiver penetration by a confined perforation of peptic ulcer is a rare but severe event. Its clinical and pathological features are unclear.
methodsIn total, 41 qualified English publications were identified using the PubMed database and one in-house case.
resultsAmong the 42 patients, 20 patients had liver involvement by a perforated duodenal ulcer and 22 by a gastric ulcer. Among the 23 cases of known ulcer histology, 2 ulcers were malignant and were adenocarcinomas in the gastric remnant and the remaining 21 ulcers were confirmed as histologically benign (for frequency of malignancy in duodenal versus gastric ulcers,
conclusionsCareful histologic examination, clinicopathological correlation, and immunohistochemistry are critical to establish the diagnosis and avoid misdiagnosing liver involvement as malignancy.
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