ArticleSTAR protocols2021
FunGraph: A statistical protocol to reconstruct omnigenic multilayer interactome networks for complex traits.
Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Graph statistics theory of individualized quantitative genetics under haplotype-resolved genome assembly.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The Genetic Architecture of Juvenile Growth Traits in the ConiferFrontiers in plant science · 2022Article
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Authors and funding
7 authors.
Funding
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Abstract
We describe a statistical protocol of how to reconstruct and dissect functional omnigenic multilayer interactome networks that mediate complex dynamic traits in a genome-wide association study (GWAS). This protocol, named FunGraph, can analyze how each locus affects phenotypic variation through its own direct effect and a complete set of indirect effects due to regulation by other loci co-existing in large-scale networks. FunGraph is applicable to any GWAS aimed to characterize the genetic architecture of dynamic phenotypic traits. For complete details on the use and execution of this protocol, please refer to Wang et al. (2021).
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Registered trials
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