Evidence map›Paper›PMID 34927090›Full record

ArticleSTAR protocols2021

Embryonic echocardiography for assessment of congenital and functional cardiac defects.

Ivan Menendez-Montes, Maria Villalba-Orero, Beatriz Escobar, Silvia Martin-Puig

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Mouse Cardiovascular Imaging.Current protocols · 2024
    Review
  2. Standardisation and future of preclinical echocardiography.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ivan Menendez-MontesVascular Pathophysiology. National Center for Cardiovascular Research. Madrid, Spain.
Maria Villalba-OreroVascular Pathophysiology. National Center for Cardiovascular Research. Madrid, Spain.
Beatriz EscobarVascular Pathophysiology. National Center for Cardiovascular Research. Madrid, Spain.
Silvia Martin-PuigVascular Pathophysiology. National Center for Cardiovascular Research. Madrid, Spain.
Spanish National Centre for Cardiovascular Research · ESConsejo Superior de Investigaciones Científicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac function and morphology by mouse fetal echocardiography can be assessed by scanning the uterus extracted from the abdominal cavity (trans-uterine ultrasound) or the womb (trans-abdominal ultrasound). Advantages of trans-abdominal ultrasound include (1) non-invasive longitudinal analysis at different stages, reducing animal use; and (2) maintenance of natural environment, diminishing perturbations on functional parameters, which are more frequent in trans-uterine conditions. Here we describe both approaches, explaining how to identify congenital cardiac defects and defining the correlation between echocardiography findings and histological analysis. For complete details on the use and execution of this protocol, please refer to (Menendez-Montes et al., 2016) and (Menendez-Montes et al., 2021).

Indexed as

AnimalsEchocardiographyEmbryo, MammalianFemaleFetal HeartHeart Defects, CongenitalImage Interpretation, Computer-AssistedMaleMicePregnancyUltrasonography, PrenatalDevelopmental biologyHealth SciencesModel Organisms

Identifiers

PMID34927090
PMCPMC8649964
OpenAlexW4200089590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.