ArticleEClinicalMedicine2022
Effect of
Article in EClinicalMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02679807 (Effect of Probiotic on Rhinovirus Induced Colds), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Probiotic on Rhinovirus Induced Colds
Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Live microbials to boost Anti-SARS-CoV-2 immunity clinical trial (Live BASIC trial): a triple-blind randomized controlled trial.Infection · 2026Trial
- The gut-lung axis and viral pneumonia: Unrevealing the gut microbiota.Pharmaceutical science advances · 2026Review
- Comparative Immunomodulatory Profiles ofJournal of microbiology and biotechnology · 2026Article
- In vitro assessment of the impact of astragalus, pineapple stem and bergamot extracts on human fecal bacteria.BMC complementary medicine and therapies · 2026Article
- The effect of probioticHeliyon · 2024Article
- The Effect ofMicroorganisms · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was designed to assess the efficacy of
methodsThe effect of ingestion of the probiotic Bl-04 was evaluated in a randomized, double-blinded rhinovirus (RV) challenge study. Healthy volunteers recruited from a university community in USA were randomized 1:1 using a computer generated code to ingest either Bl-04 (n=165) or placebo (n=169) for 28 days and were then challenged with RV-A39, and followed for 14 days. All study interactions and sample collection occurred in dedicated clinical research space. The primary analysis was the effect of the probiotic on the incidence of RV-associated illness. (Trial registration: NCT02679807, study complete).
findingsThe first cohort of volunteers was randomized on March 14, 2016 and the last (5
interpretationIn this study there was no effect of orally administered Bl-04 on the occurrence of RV-associated illness.
fundingDanisco Sweeteners Oy (now IFF Health & Biosciences).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.