Evidence map›Paper›PMID 34926992›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2022

Minnesota COVID-19 Lockdowns: The Effect on Acute Myocardial Infarctions and Revascularizations in the Community.

Guilherme S Lopes, Sheila M Manemann, Susan A Weston, Ruoxiang Jiang, Nicholas B Larson, Ethan D Moser, Véronique L Roger, Paul Y Takahashi, Yader Sandoval, Malcolm R Bell and 5 more

Open access · goldAbstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Health Care Utilization and Death in Patients With Heart Failure During the COVID-19 Pandemic.Mayo Clinic proceedings. Innovations, quality & outcomes · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Guilherme S LopesDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Sheila M ManemannDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Susan A WestonDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Ruoxiang JiangDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Nicholas B LarsonDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Ethan D MoserDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Véronique L RogerDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Paul Y TakahashiDivision of Community Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN.
Yader SandovalDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Malcolm R BellDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Alanna M ChamberlainDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
LaPrincess C BrewerDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Mandeep SinghDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Jennifer L St SauverDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Suzette J BielinskiDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Mayo Clinic in Florida · USMayo Clinic in Arizona · USNational Institutes of Health · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
CARDIOVASOLOGYT32HL007111 · NHLBI · MAYO CLINIC ROCHESTER · PI Barry A. Borlaug · 1985 to 2026
$8.7M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NHLBI NIH HHS T32 HL007111NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

objectiveTo study associations between the Minnesota coronavirus disease 2019 (COVID-19) mitigation strategies on incidence rates of acute myocardial infarction (MI) or revascularization among residents of Southeast Minnesota.

methodsUsing the Rochester Epidemiology Project, all adult residents of a nine-county region of Southeast Minnesota who had an incident MI or revascularization between January 1, 2015, and December 31, 2020, were identified. Events were defined as primary in-patient diagnosis of MI or undergoing revascularization. We estimated age- and sex-standardized incidence rates and incidence rate ratios (IRRs) stratified by key factors, comparing 2020 to 2015-2019. We also calculated IRRs by periods corresponding to Minnesota's COVID-19 mitigation timeline: "Pre-lockdown" (January 1-March 11, 2020), "First lockdown" (March 12-May 31, 2020), "Between lockdowns" (June 1-November 20, 2020), and "Second lockdown" (November 21-December 31, 2020).

resultsThe incidence rate in 2020 was 32% lower than in 2015-2019 (24 vs 36 events/100,000 person-months; IRR, 0.68; 95% CI, 0.62-0.74). Incidence rates were lower in 2020 versus 2015-2019 during the first lockdown (IRR, 0.54; 95% CI, 0.44-0.66), in between lockdowns (IRR, 0.70; 95% CI, 0.61-0.79), and during the second lockdown (IRR, 0.54; 95% CI, 0.41-0.72). April had the lowest IRR (IRR 0.48; 95% CI, 0.34-0.68), followed by August (IRR, 0.55; 95% CI, 0.40-0.76) and December (IRR, 0.56; 95% CI, 0.41-0.77). Similar declines were observed across sex and all age groups, and in both urban and rural residents.

conclusionMitigation measures for COVID-19 were associated with a reduction in hospitalizations for acute MI and revascularization in Southeast Minnesota. The reduction was most pronounced during the lockdown periods but persisted between lockdowns.

Indexed as

CABG, coronary artery bypass graftCOVID-19, coronavirus disease 2019IRR, incidence rate ratioMI, myocardial infarctionPCI, percutaneous coronary interventionREP, Rochester Epidemiology Project

Identifiers

PMID34926992
PMCPMC8666289
OpenAlexW4200405915

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.