Evidence map›Paper›PMID 34926981›Full record

ArticleRheumatology advances in practice2021

Understanding flare in axial spondyloarthritis: novel insights from daily self-reported flare experience.

Rosemarie Barnett, Stanley Ng, Raj Sengupta

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Rheumatology advances in practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06967077 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Exploring the Feasibility and Acceptability of Virtual Reality Exercise for Pain Management, Fear of Movement, Mobility, and Proprioception Deficit in Axial Spondyloarthritis Patients During Flares: Twics Design

TypeinterventionalSponsorUniversity of BathRan2025 to 2027Enrolled40ConditionsAxial SpondyloarthritisArmsVirtual reality head set.
NCT07688174 active not recruitingnot on this mapstarted 2026, after this paper: background citation

Evidence Based, Patient-led Development of a Novel Axial Spondyloarthritis Flare Management Pathway

Typeobservational_patient_registrySponsorRoyal United Hospitals Bath NHS Foundation TrustRan2026 to 2026Enrolled40ConditionsAxial Spondyloarthritis (AxSpA), Axial Spondyloarthritis, Non-Radiographic, Axial Spondyloarthritis, Radiographic, Axial Spondylarthritis (r-axSpA)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Rosemarie BarnettRheumatology, Royal National Hospital for Rheumatic Diseases, Royal United Hospitals NHS Foundation Trust.ORCID https://orcid.org/0000-0002-2215-4970
Stanley NgWhite Swan Charity, Exeter.
Raj SenguptaRheumatology, Royal National Hospital for Rheumatic Diseases, Royal United Hospitals NHS Foundation Trust.ORCID https://orcid.org/0000-0002-9720-0396
Royal National Hospital for Rheumatic Diseases · GBPhillips Exeter Academy · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOur objective was to explore daily self-reported experiences of axial SpA (axSpA) flare based on data entered into the Project Nightingale smartphone app (www.projectnightingale.org), between 5 April 2018 and 1 April 2020.

methodsPaired

resultsA total of 143/189 (75.7%) participants recorded at least one flare. Each flare lasted a mean of 4.30 days (S.d. 6.82, range 1-78), with a mean frequency of once every 35.32 days (S.d. 65.73, range 1-677). Significant relationships were identified between flare status and variable scores. Two clusters of participants were identified with distinct flare profiles. Group 1 experienced less severe worsening of symptoms during flare in comparison to group 2 (

conclusionsTwo clusters of participants were identified with distinct flare experiences but similar baseline clinical characteristics. Smartphone technologies capture subtle changes in disease experience not currently considered in clinical practice.

Indexed as

ASaxial spondyloarthritisflarepatient-reported outcomesremote monitoringsymptoms

Identifiers

PMID34926981
PMCPMC8678434
OpenAlexW3210854346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.