Evidence map›Paper›PMID 34926952›Full record

ArticleACS omega2021

Hypervalent Iodine(III)-Promoted C3-H Regioselective Halogenation of 4-Quinolones under Mild Conditions.

Fang Yang, Xiaoqing Wang, Wenzhuo Zhao, Fei Yu, Zhengsen Yu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Regioselective C(spRSC advances · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fang YangThe Hebei Key Laboratory of Analysis and Control of Zoonotic Pathogenic Micro-organism, College of Life Science, Hebei Agriculture University, Baoding, Hebei 071001, People's Republic of China.
Xiaoqing WangColleges of Science, Hebei Agriculture University, Baoding, Hebei 071001, People's Republic of China.
Wenzhuo ZhaoThe Hebei Key Laboratory of Analysis and Control of Zoonotic Pathogenic Micro-organism, College of Life Science, Hebei Agriculture University, Baoding, Hebei 071001, People's Republic of China.
Fei YuThe Hebei Key Laboratory of Analysis and Control of Zoonotic Pathogenic Micro-organism, College of Life Science, Hebei Agriculture University, Baoding, Hebei 071001, People's Republic of China.
Zhengsen YuThe Hebei Key Laboratory of Analysis and Control of Zoonotic Pathogenic Micro-organism, College of Life Science, Hebei Agriculture University, Baoding, Hebei 071001, People's Republic of China.ORCID https://orcid.org/0000-0003-3102-6628
Hebei Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple and practical protocol for the C3-H regioselective halogenation of 4-quinolones by the action of potassium halide salt and PIFA/PIDA in good to excellent yields was developed. The current approach provides feasible access to the diversity of C3-halgenated 4-quinolones at room temperature with high regioselectivity and good functional group tolerance, from which bioactive compounds can be easily constructed. Moreover, the current method featured eco-friendly, operational convenience and is suitable for halogenation in a gram scale of 4-quinolones in water without sacrificing yields.

Identifiers

PMID34926952
PMCPMC8675166
OpenAlexW3214866089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.