ArticleAdvanced materials technologies2021
Biologically enhanced starch bio-ink for promoting 3D cell growth.
Article in Advanced materials technologies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Next-Generation Bioinks in 3D Bioprinting: Advances, Challenges, and Emerging Opportunities.ACS omega · 2026Review
- Pharmaceutical polymer-based hydrogels for 3D bioprinted drug delivery and tissue engineering applications.Journal of biological engineering · 2026Article
- Printing technologies for monitoring crop health.Nature communications · 2026Review
- High-throughput Generation of Collagen Microbeads for Extracellular Vesicle Production and Therapeutic Delivery.Advanced materials technologies · 2025Article
- Review
- Recent Advances in the Degradability and Applications of Tissue Adhesives Based on Biodegradable Polymers.International journal of molecular sciences · 2024Review
- Current Biomedical Applications of 3D-Printed Hydrogels.Gels (Basel, Switzerland) · 2023Review
- Biopolymers for Tissue Engineering: Crosslinking, Printing Techniques, and Applications.Gels (Basel, Switzerland) · 2023Review
- Short Peptide-Based Smart Thixotropic Hydrogels.Gels (Basel, Switzerland) · 2022Review
- Fabrication of Porous Spherical Beads from Corn Starch by Using a 3D Food Printing System.Foods (Basel, Switzerland) · 2022Article
- Using Spheroids as Building Blocks Towards 3D Bioprinting of Tumor Microenvironment.International journal of bioprinting · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The excellent rheological property has legitimated the suitability of starch hydrogel for extrusion-based 3D printing. However, the inability to promote cell attachment and migration has precluded the non-modified starch hydrogel from direct applications in the biomedical field. Herein, we develop a novel 3D printable nanocomposite starch hydrogel with highly enhanced biocompatibility for promoting 3D cell growth, by formulating with gelatin nanoparticles and collagen. The rheological evaluation reveals the shear-thinning and thixotropic properties of the starch-based hydrogel, as well as the combinatorial effect of collagen and gelatin nanoparticles on maintaining the printability and 3D shape fidelity. The homogeneous microporous structure with abundant collagen fibers and gelatin nanoparticles interlaced and supplies rich attachment sites for cell growth. Corroborated by the cell metabolic activity study, the multiplied proliferation rate of cells on the 3D printed nanocomposite starch hydrogel scaffold confirms the remarkable enhancement of biological function of developed starch hydrogel. Hence, the developed nanocomposite starch hydrogel serves as a highly desirable bio-ink for advancing 3D tissue engineering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.