Evidence map›Paper›PMID 34926761›Full record

ArticleGynecologic oncology reports2021

The anti-IgE monoclonal antibody omalizumab as adjuvant treatment in desensitization to carboplatin in patients with ovarian cancer.

Alessandra Vultaggio, Maria Cristina Petrella, Federica Tomao, Francesca Nencini, Valentina Mecheri, Andrea Marini, Margherita Perlato, Emanuele Vivarelli, Claudia De Angelis, Ilaria Ferrarini and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Gynecologic oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Review
  2. Review
  3. Review
  4. The Expanding Role of Omalizumab: From Food Allergy to Drug Desensitization.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Alessandra VultaggioImmunoallergology Unit, Careggi University Hospital, Florence, Italy.
Maria Cristina PetrellaMedical Oncology Unit, Careggi University Hospital, Florence, Italy.
Federica TomaoDepartment of Gynecologic Oncology, European Institute of Oncology (IEO), IRCSS, Milan, Italy.
Francesca NenciniImmunoallergology Unit, Careggi University Hospital, Florence, Italy.
Valentina MecheriImmunoallergology Unit, Careggi University Hospital, Florence, Italy.
Andrea MariniMedical Oncology Unit, Careggi University Hospital, Florence, Italy.
Margherita PerlatoImmunoallergology Unit, Careggi University Hospital, Florence, Italy.
Emanuele VivarelliImmunoallergology Unit, Careggi University Hospital, Florence, Italy.
Claudia De AngelisMedical Oncology Unit, Careggi University Hospital, Florence, Italy.
Ilaria FerrariniMedical Oncology Unit, Careggi University Hospital, Florence, Italy.
Serena PillozziMedical Oncology Unit, Careggi University Hospital, Florence, Italy.
Andrea MatucciImmunoallergology Unit, Careggi University Hospital, Florence, Italy.
Lorenzo AntonuzzoMedical Oncology Unit, Careggi University Hospital, Florence, Italy.
Azienda Ospedaliero-Universitaria Careggi · ITEuropean Institute of Oncology · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•Ovarian cancer is the most lethal among gynecological cancers.•Carboplatin-based chemotherapy identifies as the main systemic treatment for ovarian cancer patients.•Almost one every three patients treated with carboplatin experiences hypersensitivity reactions.•Patients may experience breakthrough reactions during drug desensitization.•Omalizumab represents a promising new treatment to overcome carboplatin hypersensitivity.

Indexed as

Drug desensitizationHypersensitivity reactionsIgE antibiodiesOmalizumabOvarian cancerPlatinum salts

Identifiers

PMID34926761
PMCPMC8651898
OpenAlexW3207874882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.