Evidence map›Paper›PMID 34926724›Full record

ArticleOptica2020

Single-pixel fluorescent diffraction tomography.

Patrick A Stockton, Jeffrey J Field, Jeff Squier, Ali Pezeshki, Randy A Bartels

Abstract read
In one paragraph

Article in Optica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Optical single-pixel volumetric imaging by three-dimensional light-field illumination.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patrick A StocktonDepartment of Electrical and Computer Engineering, Colorado State University, Fort Collins, Colorado 80523, USA.
Jeffrey J FieldDepartment of Electrical and Computer Engineering, Colorado State University, Fort Collins, Colorado 80523, USA.ORCID 0000-0003-3323-6282
Jeff SquierDepartment of Physics, Colorado School of Mines, Golden, Colorado 80401, USA.
Ali PezeshkiDepartment of Electrical and Computer Engineering, Colorado State University, Fort Collins, Colorado 80523, USA.
Randy A BartelsDepartment of Electrical and Computer Engineering, Colorado State University, Fort Collins, Colorado 80523, USA.ORCID 0000-0003-0530-0435

Funding

Deep-tissue super-resolved microscopy with multiphoton spatial frequency-modulated imaging (MP-SPIFI)R21MH117786 · NIMH · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
Unrestricted super-resolution imaging deep in tissues through scattering immune spatial frequency modulated imagingR21EB025389 · NIBIB · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
NIBIB NIH HHS R21 EB025389NIMH NIH HHS R21 MH117786
6 · The paper itself

Abstract

Optical diffraction tomography (ODT) is an indispensable tool for studying objects in three dimensions. Until now, ODT has been limited to coherent light because spatial phase information is required to solve the inverse scattering problem. We introduce a method that enables ODT to be applied to imaging incoherent contrast mechanisms such as fluorescent emission. Our strategy mimics the coherent scattering process with two spatially coherent illumination beams. The interferometric illumination pattern encodes spatial phase in temporal variations of the fluorescent emission, thereby allowing incoherent fluorescent emission to mimic the behavior of coherent illumination. The temporal variations permit recovery of the spatial distribution of fluorescent emission with an inverse scattering model. Simulations and experiments demonstrate isotropic resolution in the 3D reconstruction of a fluorescent object.

Identifiers

PMID34926724
PMCPMC8682970

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.