Evidence map›Paper›PMID 34926711›Full record

ArticleOpen forum infectious diseases2021

Value of Packaged Testing for Sexually Transmitted Infections for Persons who Inject Drugs Hospitalized With Serious Injection-Related Infections.

Laura R Marks, Hilary Reno, Stephen Y Liang, Evan S Schwarz, David B Liss, Linda Jiang, Nathanial S Nolan, Michael J Durkin

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura R MarksDivision of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-5317-443X
Hilary RenoDivision of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-4979-5492
Stephen Y LiangDivision of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Evan S SchwarzDepartment of Emergency Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
David B LissDepartment of Emergency Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Linda JiangDivision of Medical Education, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Nathanial S NolanDivision of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Michael J DurkinDivision of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.

Funding

Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
Using Implementation Science and Informatics to Develop and Pilot Test Antibiotic Stewardship Clinical Decision SupportK23DE029514 · NIDCR · WASHINGTON UNIVERSITY · PI DURKIN, MICHAEL JOSEPH · 2021 to 2025
$632k
NCATS NIH HHS KL2 TR002346NIAID NIH HHS T32 AI007172NIDCR NIH HHS K23 DE029514
6 · The paper itself

Abstract

backgroundPersons who inject drugs (PWID) are frequently admitted for serious injection-related infections (SIRIs). PWID are also at risk for sexually transmitted infections (STIs).

methodsWe conducted a multicenter quality improvement project at 3 hospitals in Missouri. PWID with SIRI who received an infectious diseases consultation were prospectively identified and placed into an electronic database as part of a Centers for Disease Control and Prevention-funded quality improvement project. Baseline data were collected from 8/1/2019 to 1/30/2020. During the intervention period (2/1/2020-2/28/2021), infectious diseases physicians caring for patients received 2 interventions: (1) email reminders of best practice screening for HIV, viral hepatitis, and STIs; (2) access to a customized EPIC SmartPhrase that included checkboxes of orders to include in assessment and plan of consultation notes. STI screening rates were compared before and after the intervention. We then calculated odds ratios to evaluate for risk factors for STIs in the cohort.

resultsThree hundred ninety-four unique patients were included in the cohort. Initial screening rates were highest for hepatitis C (88%), followed by HIV (86%). The bundled intervention improved screening rates for all conditions and substantially improved screening rates for gonorrhea, chlamydia, and syphilis (30% vs 51%, 30% vs 51%, and 39 vs 60%, respectively;

conclusionsPWID admitted for SIRI frequently have unrecognized STIs. Our bundled intervention improved STI screening rates, but additional interventions are needed to optimize screening.

Indexed as

opioid use disordersexually transmitted infectionssubstance abuseviral hepatitis

Identifiers

PMID34926711
PMCPMC8675536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.