Evidence map›Paper›PMID 34926643›Full record

ArticleFrontiers in veterinary science2021

T Cell Immune Profiles of Blood and Tumor in Dogs Diagnosed With Malignant Melanoma.

Ellen E Sparger, Hong Chang, Ning Chin, Robert B Rebhun, Sita S Withers, Hung Kieu, Robert J Canter, Arta M Monjazeb, Michael S Kent

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. A review of CD4Veterinary immunology and immunopathology · 2024
    Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ellen E SpargerDepartment of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Hong ChangCenter for Companion Animal Health, Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Ning ChinCalifornia National Primate Research Center, Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, United States.
Robert B RebhunCenter for Companion Animal Health, Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Sita S WithersDepartment of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Hung KieuDepartment of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Robert J CanterSurgical Oncology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
Arta M MonjazebRadiation Oncology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
Michael S KentCenter for Companion Animal Health, Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
University of California, Davis · USLouisiana State University · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KC KENT LLOYD · 2002 to 2026
$84.9M
Gene Expression Analysis of Dog Natural Killer Cells Following Immunotherapy with Molecularly Targeted Radionuclide therapy or Inhaled IL-15U01CA224166 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CANTER, ROBERT J., REBHUN, ROBERT B · 2017 to 2021
$3.0M
Gene Expression Analysis of Dog Natural Killer Cells as Immunotherapy TargetR03CA252793 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CANTER, ROBERT J. · 2021 to 2022
$157k
NCI NIH HHS P30 CA093373NCI NIH HHS R03 CA252793NCI NIH HHS U01 CA224166
6 · The paper itself

Abstract

Investigation of canine T cell immunophenotypes in canine melanomas as prognostic biomarkers for disease progression or predictive biomarkers for targeted immunotherapeutics remains in preliminary stages. We aimed to examine T cell phenotypes and function in peripheral blood mononuclear cells (PBMC) and baseline tumor samples by flow cytometry, and to compare patient (

Indexed as

caninecomparative oncologydogimmune profilemelanomaone health

Identifiers

PMID34926643
PMCPMC8674490
OpenAlexW3214820661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.