Evidence map›Paper›PMID 34926580›Full record

ArticleFrontiers in molecular biosciences2021

5-Methylcytosine RNA Methyltransferases-Related Long Non-coding RNA to Develop and Validate Biochemical Recurrence Signature in Prostate Cancer.

Ke Wang, Weibo Zhong, Zining Long, Yufei Guo, Chuanfan Zhong, Taowei Yang, Shuo Wang, Houhua Lai, Jianming Lu, Pengxiang Zheng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Detection, molecular function and mechanisms of m5C in cancer.Clinical and translational medicine · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Carcinogenic roles of MAFG-AS1 in human cancers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  9. LncRNA MAFG-AS1 is involved in human cancer progression.European journal of medical research · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Vital roles of mFrontiers in immunology · 2023
    Review
  15. Article
  16. Article
  17. The mFrontiers in immunology · 2023
    Article
  18. Role of main RNA modifications in cancer: NSignal transduction and targeted therapy · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ke WangDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Weibo ZhongDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Zining LongDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Yufei GuoDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Chuanfan ZhongDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Taowei YangDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Shuo WangDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Houhua LaiDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Jianming LuDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Pengxiang ZhengDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Xiangming MaoDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Southern Medical University · CNZhujiang Hospital · CNFujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of 5-methylcytosine in RNA (m5C) in various human cancers have been increasingly studied recently; however, the m5C regulator signature in prostate cancer (PCa) has not been well established yet. In this study, we identified and characterized a series of m5C-related long non-coding RNAs (lncRNAs) in PCa. Univariate Cox regression analysis and least absolute shrinkage and selector operation (LASSO) regression analysis were implemented to construct a m5C-related lncRNA prognostic signature. Consequently, a prognostic m5C-lnc model was established, including 17 lncRNAs:

Indexed as

5-methylcytosine in RNA (m5C)biochemical recurrencelncRNAprognostic modelprostate cancer

Identifiers

PMID34926580
PMCPMC8672116
OpenAlexW3216438932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.