Evidence map›Paper›PMID 34926514›Full record

ArticleFrontiers in medicine2021

Comparison of Machine Learning Approaches to Improve Diagnosis of Optic Neuropathy Using Photopic Negative Response Measured Using a Handheld Device.

Tina Diao, Fareshta Kushzad, Megh D Patel, Megha P Bindiganavale, Munam Wasi, Mykel J Kochenderfer, Heather E Moss

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tina DiaoDepartment of Management Science & Engineering, Stanford University, Stanford, CA, United States.
Fareshta KushzadDepartment of Ophthalmology, Stanford University, Palo Alto, CA, United States.
Megh D PatelDepartment of Ophthalmology, Stanford University, Palo Alto, CA, United States.
Megha P BindiganavaleDepartment of Ophthalmology, Stanford University, Palo Alto, CA, United States.
Munam WasiDepartment of Ophthalmology, Stanford University, Palo Alto, CA, United States.
Mykel J KochenderferDepartment of Ophthalmology, Stanford University, Palo Alto, CA, United States.
Heather E MossDepartment of Ophthalmology, Stanford University, Palo Alto, CA, United States.
Stanford University · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI TIRIN MOORE · 2017 to 2026
$8.0M
Physiologically Based Markers of Idiopathic Intracranial HypertensionK23EY024345 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MOSS, HEATHER ELSPETH · 2014 to 2018
$1.1M
NEI NIH HHS K23 EY024345NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

The photopic negative response of the full-field electroretinogram (ERG) is reduced in optic neuropathies. However, technical requirements for measurement and poor classification performance have limited widespread clinical application. Recent advances in hardware facilitate efficient clinic-based recording of the full-field ERG. Time series classification, a machine learning approach, may improve classification by using the entire ERG waveform as the input. In this study, full-field ERGs were recorded in 217 eyes (109 optic neuropathy and 108 controls) of 155 subjects. User-defined ERG features including photopic negative response were reduced in optic neuropathy eyes (

Indexed as

classificationelectroretinogram (ERG)machine learningoptic neuropathyphotopic negative response (PhNR)time series analysis

Identifiers

PMID34926514
PMCPMC8677942
OpenAlexW4200563939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.