Evidence map›Paper›PMID 34926328›Full record

ReviewFrontiers in cellular and infection microbiology2021

Stressed Out About

Miho Usui, Kim C Williamson

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. MaRNAV-1, an intracellular virus ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Molecular mechanisms involved inFrontiers in microbiology · 2026
    Review
  4. mBio · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Microorganisms · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Streamlined and Robust Stage-Specific Profiling of Gametocytocidal Compounds AgainstFrontiers in cellular and infection microbiology · 2022
    Article
  16. Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria Elimination.Frontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Miho UsuiDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Kim C WilliamsonDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Uniformed Services University of the Health Sciences · US

Funding

Plasmodium falciparum gametocytogenesis in vitro and in vivoR01AI147627 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI AMOAH, LINDA EVA, WILLIAMSON, KIM C · 2020 to 2024
$2.6M
Advancing gametocytocidal agents as drugs against P. falciparumR01AI114761 · NIAID · LOYOLA UNIVERSITY OF CHICAGO · PI WILLIAMSON, KIM C · 2015 to 2019
$1.9M
NIAID NIH HHS R01 AI114761NIAID NIH HHS R01 AI147627
6 · The paper itself

Abstract

Blocking malaria transmission is critical to malaria control programs but remains a major challenge especially in endemic regions with high levels of asymptomatic infections. New strategies targeting the transmissible sexual stages of the parasite, called gametocytes, are needed. This review focuses on

Indexed as

MalariaMalaria, FalciparumAnimalsAsymptomatic InfectionsLife Cycle StagesPlasmodium falciparumbone marrowdevelopmental regulationgametocytemalariasexual differentiationtransmission

Identifiers

PMID34926328
PMCPMC8674873
OpenAlexW3216234848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.