Evidence map›Paper›PMID 34926322›Full record

ArticleFrontiers in cellular and infection microbiology2021

Alpha-Gal Syndrome: Involvement of

Surendra Raj Sharma, Gary Crispell, Ahmed Mohamed, Cameron Cox, Joshua Lange, Shailesh Choudhary, Scott P Commins, Shahid Karim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

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  4. Differential alpha-gal expression duringThe journal of allergy and clinical immunology. Global · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Surendra Raj SharmaSchool of Biological, Environment and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
Gary CrispellSchool of Biological, Environment and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
Ahmed MohamedSchool of Biological, Environment and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
Cameron CoxSchool of Biological, Environment and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
Joshua LangeSchool of Biological, Environment and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
Shailesh ChoudharyDepartment of Medicine and Pediatrics, University of North Carolina, Chapel Hill, NC, United States.
Scott P ComminsDepartment of Medicine and Pediatrics, University of North Carolina, Chapel Hill, NC, United States.
Shahid KarimSchool of Biological, Environment and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
University of Southern Mississippi · USUniversity of North Carolina at Chapel Hill · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Understanding alpha-gal red meat allergyR01AI135049 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott Palmer Commins · 2018 to 2026
$5.1M
NIAID NIH HHS R01 AI135049NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P20 GM104357
6 · The paper itself

Abstract

Alpha-Gal Syndrome (AGS) is an IgE-mediated delayed-type hypersensitivity reaction to the oligosaccharide galactose-α-1, 3-galactose (α-gal) injected into humans from the lone-star tick (

Indexed as

AmblyommaImmunoglobulin Ealpha-GalactosidaseAnimalsFood HypersensitivityGalactosidasesGalactosyltransferasesHumansalpha-GalactosidaseGalactosidasesGalactosyltransferasesImmunoglobulin E4 galactosyltransferasealpha-D-galactosidasealpha-galalpha-gal syndromebeta-1N-glycanred meat allergytick

Identifiers

PMID34926322
PMCPMC8671611
OpenAlexW3216574794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.