Evidence map›Paper›PMID 34926287›Full record

ArticleFrontiers in oncology2021

A Bounding Box-Based Radiomics Model for Detecting Occult Peritoneal Metastasis in Advanced Gastric Cancer: A Multicenter Study.

Dan Liu, Weihan Zhang, Fubi Hu, Pengxin Yu, Xiao Zhang, Hongkun Yin, Lanqing Yang, Xin Fang, Bin Song, Bing Wu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Dan LiuDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Weihan ZhangDepartment of Gastrointestinal Surgery and Laboratory of Gastric Cancer, Collaborative Innovation Center for Biotherapy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Fubi HuDepartment of Radiology, First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Pengxin YuInstitute of Advanced Research, Infervision, Beijing, China.
Xiao ZhangDepartment of Radiology, People's Hospital of Leshan, Leshan, China.
Hongkun YinInstitute of Advanced Research, Infervision, Beijing, China.
Lanqing YangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Xin FangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Bin SongDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Bing WuDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Jiankun HuDepartment of Gastrointestinal Surgery and Laboratory of Gastric Cancer, Collaborative Innovation Center for Biotherapy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Zixing HuangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CNInferVision (China) · CNFirst Affiliated Hospital of Chengdu Medical College · CNPeople's Hospital of Bishan District · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop a bounding box (BBOX)-based radiomics model for the preoperative diagnosis of occult peritoneal metastasis (OPM) in advanced gastric cancer (AGC) patients. MATERIALS AND

methods599 AGC patients from 3 centers were retrospectively enrolled and were divided into training, validation, and testing cohorts. The minimum circumscribed rectangle of the ROIs for the largest tumor area (R_BBOX), the nonoverlapping area between the tumor and R_BBOX (peritumoral area; PERI) and the smallest rectangle that could completely contain the tumor determined by a radiologist (M_BBOX) were used as inputs to extract radiomic features. Multivariate logistic regression was used to construct a radiomics model to estimate the preoperative probability of OPM in AGC patients.

resultsThe M_BBOX model was not significantly different from R_BBOX in the validation cohort [AUC: M_BBOX model 0.871 (95% CI, 0.814-0.940)

conclusionsThe BBOX-based radiomics could serve as a simpler reliable and powerful tool for the preoperative diagnosis of OPM in AGC patients. And M_BBOX-based radiomics is simpler and less time consuming.

Indexed as

bounding boxcomputed tomographygastric cancerperitoneal metastasisradiomics

Identifiers

PMID34926287
PMCPMC8678129
OpenAlexW4200095559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.