Evidence map›Paper›PMID 34926240›Full record

ArticleFrontiers in oncology2021

MRI-Based Bone Marrow Radiomics Nomogram for Prediction of Overall Survival in Patients With Multiple Myeloma.

Yang Li, Yang Liu, Ping Yin, Chuanxi Hao, Chao Sun, Lei Chen, Sicong Wang, Nan Hong

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. BMC medical imaging · 2023
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang LiDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Yang LiuPeking University Institute of Hematology, Peking University People's Hospital, Beijing, China.
Ping YinDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Chuanxi HaoDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Chao SunDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Lei ChenDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Sicong WangPharmaceutical Diagnostics, GE Healthcare, Shanghai, China.
Nan HongDepartment of Radiology, Peking University People's Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop and validate a radiomics nomogram for predicting overall survival (OS) in multiple myeloma (MM) patients. MATERIAL AND

methodsA total of 121 MM patients was enrolled and divided into training (n=84) and validation (n=37) sets. The radiomics signature was established by the selected radiomics features from lumbar MRI. The radiomics signature and clinical risk factors were integrated in multivariate Cox regression model for constructing radiomics nomogram to predict MM OS. The predictive ability and accuracy of the nomogram were evaluated by the index of concordance (C-index) and calibration curves, and compared with other four models including the clinical model, radiomics signature model, the Durie-Salmon staging system (D-S) and the International Staging System (ISS). The potential association between the radiomics signature and progression-free survival (PFS) was also explored.

resultsThe radiomics signature, 1q21 gain, del (17p), and β2-MG≥5.5 mg/L showed significant association with MM OS. The predictive ability of radiomics nomogram was better than the clinical model, radiomics signature model, the D-S and the ISS (C-index: 0.793

conclusionThe MRI-based bone marrow radiomics may be an additional useful tool for MM OS prediction.

Indexed as

magnetic resonance imagingmultiple myelomanomogramradiomicssurvival

Identifiers

PMID34926240
PMCPMC8671997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.