ArticleInternational journal of ophthalmology2021
Clinical analysis of 109 cases of lacrimal gland pleomorphic adenoma.
Article in International journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Partial orbital lobe dacryoadenectomy for refractory epiphora.Indian journal of ophthalmology · 2026Article
- Diagnostic and Surgical Challenges in Lacrimal Gland Pleomorphic Adenoma: A Case With Prolonged Ptosis and Acute Orbital Changes.Case reports in medicine · 2026Article
- Bone alterations in head and neck pleomorphic adenoma: Scoping review.Oral radiology · 2025Article
- Lacrimal gland pleomorphic adenoma: two referral center analyses in Hokkaido, Japan.International journal of ophthalmology · 2025Article
- Clinical features and prognosis of carcinoma ex pleomorphic adenoma of the lacrimal gland: a comprehensive case series and literature review.International journal of ophthalmology · 2025Article
- Long-term follow-up of tracheal pleomorphic adenoma: A case report.Respiratory medicine case reports · 2024Article
- Frontal Bone Osteotomy for Excision of Large Lacrimal Gland Pleomorphic Adenoma: A Rare Case Report.Journal of maxillofacial and oral surgery · 2023Article
- Preliminary proteomic analysis of human tears in lacrimal adenoid cystic carcinoma and pleomorphic adenoma.International journal of ophthalmology · 2023Article
- Adenoid Cystic Carcinoma of the Lacrimal Gland.Journal of current ophthalmologyReview
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Authors and funding
5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
aimTo monitor the prognosis of patients with lacrimal gland pleomorphic adenoma (LGPA) following surgical resection within the past 10y. The factors affecting patient prognosis are analyzed and the experience of surgical treatment is summarized.
methodsIn this retrospective, comparative case series, clinical records from 109 cases of LGPA treated chiefly at the same institution between November 2009 and May 2019 were reviewed. All 109 patients underwent surgery, histopathological examination, and imaging examination. For patients who underwent surgery for the first time, LGPA could be resected completely, including tumor and capsule tissues, using a surgical approach
resultsThe ratio of males to females was 1:1.60, the ages ranged from 19 to 74 years old with a mean age of 43.64±13.07 years old, and the ratio of left to right eyes was 1:1.37. A total of 109 patients underwent surgical excision and five of these received radiotherapy after malignant transformation. Of these patients, 15 were lost to follow up within the April 1, 2020 deadline and 1 was diagnosed as a recurring pathology. The 5-year recurrence rate for 86 patients who underwent initial surgery was 7.27%. Single factor analysis revealed that the course of disease, bone destruction, invasion of surrounding tissues, tumor size, capsule integrity, and expression of Ki-67 were statistically significant (
conclusionLGPA has a risk of recurrence and potential for malignant transformation. Complete removal of the tumor and capsule in the initial surgery is a key factor in preventing recurrence.
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