Evidence map›Paper›PMID 34926161›Full record

ArticleUrology case reports2022

Management of SHDB positive patient with metastatic bilateral giant retroperitoneal paragangliomas.

David Strauss, Andres Correa, Yulan Gong, Andreas Karachristos, Alexander Kutikov

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

David StraussDivision of Urologic Oncology, Department of Surgery, Fox Chase Cancer Center-Temple University Health System, Philadelphia, PA, USA.
Andres CorreaDivision of Urologic Oncology, Department of Surgery, Fox Chase Cancer Center-Temple University Health System, Philadelphia, PA, USA.
Yulan GongDepartment of Pathology, Fox Chase Cancer Center-Temple University Health System, Philadelphia, PA, USA.
Andreas KarachristosDivision of Surgical Oncology, Department of Surgery, Tampa General Hospital - University of Southern Florida Health System, Tampa, FL, USA.
Alexander KutikovDivision of Urologic Oncology, Department of Surgery, Fox Chase Cancer Center-Temple University Health System, Philadelphia, PA, USA.
Fox Chase Cancer Center · USTampa General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paragangliomas are rare neuroendocrine tumors that can vary in size and metabolic activity. We report a case of giant bilateral malignant retroperitoneal paragangliomas (PGL) in a patient with germline succinate dehydrogenase B (SDHB) mutation. This patient, who presented in an emaciated and debilitated state, was managed with adrenergic blockade followed by radical primary surgery. After being metabolically and radiographically disease free for 4 years, he underwent salvage resection for recurrent retroperitoneal disease and palliative radiation to a site of solidary vertebral metastasis. We review incidence and prognosis of metastatic PGL.

Indexed as

Giant paragangliomaParaganglioma, (PGL)RetroperitonealSuccinate dehydrogenase B subunit, (SDHB)Succinate dehydrogenase mutationSuccinate dehydrogenase, (SDH)

Identifiers

PMID34926161
PMCPMC8649644
OpenAlexW3216740034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.