Evidence map›Paper›PMID 34926146›Full record

ArticleJournal of clinical orthopaedics and trauma2022

Cell therapy for osteonecrosis of femoral head and joint preservation.

You Seung Chun, Dong Hwan Lee, Tae Gu Won, Chan Sik Kim, Asode Ananthram Shetty, Seok Jung Kim

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical orthopaedics and trauma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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  6. Non-arthroplasty options for hip, knee and ankle arthritis in adults.Journal of clinical orthopaedics and trauma · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

You Seung ChunDepartment of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Dong Hwan LeeDepartment of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Tae Gu WonDepartment of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Chan Sik KimDepartment of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Asode Ananthram ShettyCanterbury Christ Church University, Faculty of Medicine, Health and Social Care, 30 Pembroke Court, Chatham Maritime, Kent, ME4 4UF, United Kingdom.
Seok Jung KimDepartment of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Catholic University of Korea · KRCanterbury Christ Church University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteonecrosis of femoral head (ONFH) is a disease of the femoral head and can cause femoral head collapse and arthritis. This can lead to pain and gait disorders. ONFH has various risk factors, it is often progressive, and if untreated results in secondary osteo-arthritis. Biological therapy makes use of bone marrow concentrate, cultured osteoblast and mesenchymal stem cell (MSC) obtained from various sources. These are often used in conjunction with core decompression surgery. In this review article, we discuss the current status of cell therapy and its limitations. We also present the future development of biological approach to treat ONFH.

Indexed as

Cell therapyCore decompressionFemoral headOsteonecrosisPathogenesisStem cell

Identifiers

PMID34926146
PMCPMC8646149
OpenAlexW3216247851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.