Evidence map›Paper›PMID 34926144›Full record

ArticleLeukemia research reports2021

Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience.

Kanta Devi, Muhammad Usman Shaikh, Natasha Bahadur Ali, Salman Naseem Adil, Maria Khan, Salman Muhammad Soomar

Open access · goldAbstract read
In one paragraph

Article in Leukemia research reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kanta DeviDepartment of Oncology, Aga Khan University Hospital Karachi, Pakistan.
Muhammad Usman ShaikhDepartment of Pathology and Laboratory Medicine, Aga Khan University Hospital Karachi, Pakistan.
Natasha Bahadur AliDepartment of Pathology and Laboratory Medicine, Aga Khan University Hospital Karachi, Pakistan.
Salman Naseem AdilDepartment of Pathology and Laboratory Medicine, Aga Khan University Hospital Karachi, Pakistan.
Maria KhanMedical College, Aga Khan University Karachi, Pakistan.
Salman Muhammad SoomarMedical College, Aga Khan University Karachi, Pakistan.
Aga Khan University Hospital · PKAga Khan University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Pakistan 76.4% of all NHLs to be diagnosed as DLBCLs. The survival of R-CHOP is better compared to the DA-REPOCH treatment regimen. A prospective follow-up study was conducted with 113 patients to study the outcomes of treatment. Multivariable cox-proportional hazard model was used to estimate the hazard ratios in patients receiving these treatment regimens considering p-value ≤0.05 significant. The survival rate among double/triple expressor lymphoma patients received R-DA-EPOCH was 82.8%, and 83.3% received R-CHOP. For double/triple expressor lymphoma patients received R-DA-EPOCH. The findings of our study demonstrated that the survival rate in both R-CHOP and R-DA-EPOCH is mostly similar.

Indexed as

COO, Cell of OriginDiffuse large B-cell lymphomaDLBCL, Diffuse large B-cell LymphomaNon-hodgkin lymphomaOS, Overall SurvivalPFS, Progression Free SurvivalR-CHOPR-CHOP, rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisoneR-DA-EPOCHR-DA-EPOCH, rituximab, dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicinSurvivalWHO, World Health Organization

Identifiers

PMID34926144
PMCPMC8648798
OpenAlexW3216223150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.