Evidence map›Paper›PMID 34926141›Full record

ArticleClinical plasma medicine2019

Innovative Cold Atmospheric Plasma (iCAP) Decreases Mucopurulent Corneal Ulcer Formation and Edema and Reduces Bacterial Load in

Wahaj Saleem, Angela H Benton, Mary E Marquart, Shuli Wang, Waqas Saleem, Randy Vigil, Bo Huang, Anjal C Sharma

Open access · greenAbstract read
In one paragraph

Article in Clinical plasma medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Argon cold atmospheric plasma eradicates pathogensFrontiers in veterinary science · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wahaj Saleem *Experimental Therapeutics and Diagnostics Group, Lynntech, Inc., 2501 Earl Rudder Fwy S., College Station, TX 77845, USA.
Angela H Benton *Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Mary E MarquartDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Shuli WangExperimental Therapeutics and Diagnostics Group, Lynntech, Inc., 2501 Earl Rudder Fwy S., College Station, TX 77845, USA.
Waqas SaleemExperimental Therapeutics and Diagnostics Group, Lynntech, Inc., 2501 Earl Rudder Fwy S., College Station, TX 77845, USA.
Randy VigilExperimental Therapeutics and Diagnostics Group, Lynntech, Inc., 2501 Earl Rudder Fwy S., College Station, TX 77845, USA.
Bo HuangDepartment of Ophthalmology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Anjal C SharmaExperimental Therapeutics and Diagnostics Group, Lynntech, Inc., 2501 Earl Rudder Fwy S., College Station, TX 77845, USA.
Lynntech (United States) · USUniversity of Mississippi Medical Center · USJackson Memorial Hospital · US

Funding

iCAP An Innovative Device to Rapidly Resolve Microbial KeratitisR43EY026824 · NEI · LYNNTECH, INC. · PI SHARMA, ANJAL C · 2016 to 2016
$237k
NEI NIH HHS R43 EY026824
6 · The paper itself

Abstract

purposeTo evaluate the effect of application of 3% air in helium cold atmospheric plasma jet, using an inexpensive device termed iCAP, in corneal scratch wound closure

methodsThermal imaging to measure temperature of surfaces to which iCAP was applied and UV energy density delivered by iCAP were measured. Scratch wounds inflicted on

resultsiCAP was shown to operate in the non-thermal regime and also shown to deliver much lower UV energy density than that necessary to cause harmful effects on ocular tissue. iCAP treatment significantly improved the rate of scratch wound gap closure

conclusionOur results strongly suggest that iCAP treatment was effective in improving corneal epithelial defect closure

Indexed as

Bacterial keratitisBacterial load reductionCold atmospheric plasmaCorneal epithelial defect closurePseudomonas aeruginosaUlcer and inflammation reduction

Identifiers

PMID34926141
PMCPMC8681885
OpenAlexW2996833909

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.