Evidence map›Paper›PMID 34926070›Full record

ArticleCureus2021

An Unusual Case of Concurrent Herpes Simplex Virus Type 1 and Cytomegalovirus Encephalitis Complicated by Primary Central Nervous System Lymphoma as an Initial Presentation of Acquired Immunodeficiency Syndrome.

Dawood Findakly

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Dawood FindaklyHematology and Medical Oncology, Louisiana State University Health Sciences Center, Shreveport, USA.
Louisiana State University Health Sciences Center Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary central nervous system lymphoma (PCNSL) is an uncommon brain tumor with a puzzling diagnosis. It has an incidence of seven cases per 100,000,000 people in the United States, which is further lower in immunocompromised patients. Cytomegalovirus (CMV) is a common cause of various malignancies, notably Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin's lymphomas, and non-Hodgkin's lymphomas (NHL) including PCNSL. Cases with PCNSL can vary in presentation with either focal or non-focal manifestations progressively worsening over a period that could last up to a few months. In this report, we discuss the case of a 39-year-old woman with a past medical history of bipolar disorder who presented with PCNSL as the initial presentation of acquired immunodeficiency syndrome (AIDS). This case report emphasizes the importance of a multidisciplinary team (MDT) approach for the interpretation as well as for correlating the laboratory and imaging results with clinical findings given the challenging diagnosis, to choose an appropriate management approach that is tailored to the patient's presentation.

Indexed as

aidsbrain biopsychemotherapyhiv-directed therapyprimary central nervous system lymphoma

Identifiers

PMID34926070
PMCPMC8674010
OpenAlexW3214394907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.