Evidence map›Paper›PMID 34925703›Full record

ArticleInternational IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering2021

A Diagnostic Circuit for Crosstalk Detection in Microelectrode Arrays.

Morgan McNamara, Alpaslan Ersöz, Martin Han

Abstract read
In one paragraph

Article in International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Morgan McNamaraBiomedical Engineering Department, University of Connecticut, Storrs, CT 06269 USA.
Alpaslan ErsözBiomedical Engineering Department, University of Connecticut, Storrs, CT 06269 USA.
Martin HanBiomedical Engineering Department, University of Connecticut, Storrs, CT 06269 USA.

Funding

Towards Clinical Translation of Penetrating Multisite Device for Cochlear NucleusR01DC014044 · NIDCD · UNIVERSITY OF CONNECTICUT STORRS · PI HAN, MARTIN · 2015 to 2019
$1.9M
Chronically-Implantable Multisite Microelectrode ArraysR24NS086603 · NINDS · HUNTINGTON MEDICAL RESEARCH INSTITUTES · PI HAN, MARTIN · 2015 to 2016
$842k
NIDCD NIH HHS R01 DC014044NINDS NIH HHS R24 NS086603
6 · The paper itself

Abstract

Current leakage between channels in microelectrode arrays is a sign of device failure and can lead to shorting of neural signals. The purpose of this project is to detect crosstalk between 32 channels of electrodes. We designed an embedded crosstalk detection system that can stimulate each electrode individually with a constant-current pulse and record voltage transients of the stimulated and adjacent electrodes to generate a matrix of crosstalk values. Charge injection in a phosphate buffered saline solution was used to check the condition of each electrode. A semi-wet condition was then used to determine the percent crosstalk between the channels. The analysis showed that there was minimal crosstalk between the electrodes, except for a known physical defect on the probe. The measurement technique enabled by the electronics circuit has the potential to be used in functional testing and screening of implantable devices.

Identifiers

PMID34925703
PMCPMC8674810

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.