Evidence map›Paper›PMID 34925606›Full record

ArticleMaedica2021

Radiomics in Head and Neck Cancers Radiotherapy. Promises and Challenges.

Roxana Irina Iancu, A D Zara, C C Mirestean, D P T Iancu

Abstract readEditorial
In one paragraph

Article in Maedica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roxana Irina Iancu"Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
A D ZaraRegional Institute of Oncology, Iasi, Romania.
C C MiresteanUniversity of Medicine and Pharmacy of Craiova, Craiova, Romania.
D P T Iancu"Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiomics, a subdomain of artificial intelligence, consists in extracting a large volume of data from all medical imaging techniques and correlating them with clinical data in order to build predictive and prognostic models. Radiomics is related to radiogenomics that correlates genetic mutations and molecular and biological characteristics of tissues with information extracted from medical imaging. Both are state-of-the-art fields of translational biomedical research. The ability to predict early patient survival and response to treatment, but also the capacity to identify tumor subtypes non-invasively, could make radiomics a key player with an essential role in personalized oncology. In head and neck cancer radiotherapy, radiomic algorithms can predict not only the response to radiochemotherapy or induction chemotherapy but also the need for planning through adaptive radiotherapy (ART). Radiomics can also predict the risk of severe toxicities, especially that of xerostomia. Given the benefit that a de-escalation of treatment can bring in selected cases to improve the quality of life, radiomics is expected to be part of the therapeutic decision for head and neck cancers in the near future, and may help identify cases where de-escalation of multimodal therapy will not jeopardize the therapeutic benefit.

Identifiers

PMID34925606
PMCPMC8643547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.