Evidence map›Paper›PMID 34925349›Full record

ArticleFrontiers in immunology2021

Effect of Extracellular Vesicles Derived From

Haining Hao, Xinyi Zhang, Lingjun Tong, Qiqi Liu, Xi Liang, Yushan Bu, Pimin Gong, Tongjie Liu, Lanwei Zhang, Yongjun Xia and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 1 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 1 synthesis or guideline pooled it, 222 citations in OpenAlex.

  1. Pooled it
  2. Synthetic and systems biotechnology · 2027
    Review
  3. Review
  4. Applied and environmental microbiology · 2026
    Article
  5. Article
  6. Article
  7. Extracellular Vesicles fromPathogens (Basel, Switzerland) · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Nutrients · 2026
    Article
  14. Article
  15. Article
  16. Protective Effects of RecombinantAnimals : an open access journal from MDPI · 2026
    Article
  17. Article
  18. Review
  19. Review
  20. Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Haining HaoCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Xinyi ZhangCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Lingjun TongCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Qiqi LiuCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Xi LiangCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Yushan BuCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Pimin GongCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Tongjie LiuCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Lanwei ZhangCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Yongjun XiaShanghai Engineering Research Center of Food Microbiology, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Lianzhong AiShanghai Engineering Research Center of Food Microbiology, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Huaxi YiCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Ocean University of China · CNUniversity of Shanghai for Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics plays an important role in regulating gut microbiota and maintaining intestinal homeostasis. Extracellular vesicles (EVs) derived from probiotics have emerged as potential mediators of host immune response and anti-inflammatory effect. However, the anti-inflammatory effect and mechanism of probiotics derived EVs on inflammatory bowel disease (IBD) remains unclear. In this study, the effect of

Indexed as

ProbioticsAnimalsColitis, UlcerativeColonDextran SulfateDisease Models, AnimalExtracellular VesiclesFecesGastrointestinal MicrobiomeHumansIntestinal MucosaLactiplantibacillus plantarumMaleMiceDextran Sulfateextracellular vesiclesgut microbiotainflammatory cytokinesLactobacillus plantarum Q7ulcerative colitis

Identifiers

PMID34925349
PMCPMC8674835
OpenAlexW4200012230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.