Evidence map›Paper›PMID 34925321›Full record

ArticleFrontiers in immunology2021

Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation.

Kathleen Santamaria, Fabienne Desmots, Simon Leonard, Gersende Caron, Marion Haas, Céline Delaloy, Fabrice Chatonnet, Delphine Rossille, Amandine Pignarre, Céline Monvoisin and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Kathleen SantamariaUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Fabienne DesmotsUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Simon LeonardUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Gersende CaronUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Marion HaasUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Céline DelaloyUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Fabrice ChatonnetUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Delphine RossilleUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Amandine PignarreUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Céline MonvoisinUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Marine SeffalsUniversity of Rennes 1, UMS Biosit, H2P2 Platform, Rennes, France.
Claire LamaisonUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Michel CognéUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Karin TarteUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Thierry FestUMR 1236, University of Rennes 1, INSERM, Établissement Français du Sang Bretagne, Rennes, France.
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B cell affinity maturation occurs in the germinal center (GC). Light-zone (LZ) GC B cells (B

Indexed as

B-LymphocytesCell DifferentiationGerminal CenterHumansLymphocyte ActivationPlasma CellsReceptors, IgETranscription, GeneticReceptors, IgEB cell differentiationCD23+ B cellsGC Light-Zone B cellsgerminal center (GC)germinal center (GC) B cellsplasmablasts/plasma cells

Identifiers

PMID34925321
PMCPMC8674954
OpenAlexW4200438125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.