Evidence map›Paper›PMID 34925005›Full record

ArticleFrontiers in pharmacology2021

The Anti-Inflammatory and Anti-Pruritus Mechanisms of Huanglian Jiedu Decoction in the Treatment of Atopic Dermatitis.

Yubin Xu, Saizhen Chen, Lingling Zhang, Guirong Chen, Jinguang Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Synthesis,Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Treatment Options for Troublesome Itch.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  11. Frontiers in nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yubin XuDepartment of Pharmacy, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.
Saizhen ChenDepartment of Pharmacy, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.
Lingling ZhangDepartment of Pharmacy, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.
Guirong ChenCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Jinguang ChenDepartment of Dermatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.
Taizhou Central Hospital · CNLiaoning University of Traditional Chinese Medicine · CNTaizhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a common chronic skin disease driven by a T-cell-mediated immune response, with inflammation and pruritus being its main clinical manifestations. Huanglian Jiedu decoction (HLJDT), which is an ancient Chinese medicine herbal formula derived from

Indexed as

atopic dermatitisHuanglian Jiedu decoctioninflammationpruritusskin disease

Identifiers

PMID34925005
PMCPMC8675233
OpenAlexW3215278589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.