Evidence map›Paper›PMID 34924959›Full record

ArticleFrontiers in cellular neuroscience2021

A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile.

Zhongrui Liu, Ziting Zhu, Yan He, Qiyun Kang, Fei Li, Wenlong Zhang, Yuehua He, Yuwan Lin, Baoyi Huang, Mingshu Mo and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Black gas, bright future: HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Zhongrui LiuDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Ziting ZhuDepartment of Neurology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Yan HeDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Qiyun KangDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Fei LiDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Wenlong ZhangDepartment of Neurology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Yuehua HeDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Yuwan LinDepartment of Neurology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Baoyi HuangDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Mingshu MoDepartment of Neurology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Pingyi XuDepartment of Neurology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Xiaoqin ZhuDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
First Affiliated Hospital of Guangzhou Medical University · CNSecond Affiliated Hospital of Guangzhou Medical University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although epilepsy is one of the most common neurologic disorders, there is still a lack of effective therapeutic drugs for it. Recently, we synthesized a novel hydrogen sulfide (H

Indexed as

hydrogen sulfide donorinflammatory profileneuroinflammationpilocarpinestatus epilepticus (SE)

Identifiers

PMID34924959
PMCPMC8674866
OpenAlexW4200531611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.