Evidence map›Paper›PMID 34924761›Full record

ArticleAdvances and applications in bioinformatics and chemistry : AABC2021

Antibacterial, Docking, DFT and ADMET Properties Evaluation of Chalcone-Sulfonamide Derivatives Prepared Using ZnO Nanoparticle Catalysis.

Abdanne Weyesa, Rajalakshmanan Eswaramoorthy, Yadessa Melaku, Endale Mulugeta

Open access · goldAbstract read
In one paragraph

Article in Advances and applications in bioinformatics and chemistry : AABC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Abdanne WeyesaDepartment of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.
Rajalakshmanan EswaramoorthyDepartment of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.ORCID 0000-0002-8331-2100
Yadessa MelakuDepartment of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.
Endale MulugetaDepartment of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.ORCID 0000-0002-2869-0934
Adama Science and Technology University · ETSaveetha University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn the present work, two novel compounds were synthesized using zinc oxide nanoparticles through green synthesis protocol. The zinc oxide nanoparticles catalyzed reactions were afforded good to excellent yields of the target compounds 76.3-98.6%. METHODOLOGY: The synthesized compounds were characterized by UV-Vis, IR and NMR. The antibacterial activity of the synthesized compounds was screened against two Gram-positive bacteria ( RESULTS AND DISCUSSION: The synthesized compounds displayed potent activity against the bacterial strains. Among them, compound

conclusionThe findings of the in vitro antibacterial and molecular docking analysis demonstrated that the synthesized compounds have potential of antibacterial activity and can be further optimized to serve as a lead compound.

Indexed as

ADMET and antibacterialchalconegreen synthesisinhibition zonemolecular dockingsulfonamideZnO nanoparticles

Identifiers

PMID34924761
PMCPMC8674577
OpenAlexW4200564924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.