ReviewPhysiology and molecular biology of plants : an international journal of functional plant biology2021
microRNA 166: an evolutionarily conserved stress biomarker in land plants targeting HD-ZIP family.
Review in Physiology and molecular biology of plants : an international journal of functional plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- What Do We Know about Barley miRNAs?International journal of molecular sciences · 2022Pooled it
- Chrysanthemum miR166 functions as a positive regulator in the salt stress response of Arabidopsis thaliana.BMC plant biology · 2026Article
- Allopolyploidization-driven short-term evolution of miRNAs in Brassica A genome.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Molecular mechanisms of bamboo-derived miRNA-mediated gene regulation and dietary adaptation in giant pandas.BMC genomics · 2025Article
- PagMIR166c targets PagECH2 to regulate cambial differentiation into secondary xylem, cell expansion, and lignin deposition via different auxin signaling pathways in poplar stems.The New phytologist · 2025Article
- Exploring the drought-responsive miRNAs and their corresponding target genes in chickpea root tissue.Plant molecular biology · 2025Article
- Characterization of Exosome-like Nanoparticles from Saffron Tepals and Their Immunostimulatory Activity.Biology · 2025Article
- Article
- Deep short-read sequences facilitated identification of seven putative drought tolerance genes in a genome-wide association study in soybean.Frontiers in plant science · 2025Article
- New insights into the salt-responsive regulation in eelgrass at transcriptional and post-transcriptional levels.Frontiers in plant science · 2025Article
- RNA Metabolism and the Role of Small RNAs in Regulating Multiple Aspects of RNA Metabolism.Non-coding RNA · 2024Review
- Genome-Wide Transcriptional Response of Avocado toPlants (Basel, Switzerland) · 2024Article
- Source leaves are regulated by sink strengths through non-coding RNAs and alternative polyadenylation in cucumber (Cucumis sativus L.).BMC plant biology · 2024Article
- Unravelling the Epigenetic Code: DNA Methylation in Plants and Its Role in Stress Response.Epigenomes · 2024Review
- Mechanism of action of microRNA166 on nitric oxide in alfalfa (Medicago sativa L.) under drought stress.BMC genomics · 2024Article
- Identification of Tomato microRNAs in Late Response toInternational journal of molecular sciences · 2024Article
- Identification and Expression Analysis of the Nucleotidyl Transferase Protein (NTP) Family in Soybean (International journal of molecular sciences · 2024Article
- Article
- Photosynthesis Response and Transcriptional Analysis: Dissecting the Role of SlHB8 in Regulating Drought Resistance in Tomato Plants.International journal of molecular sciences · 2023Article
- Functional role of microRNA in the regulation of biotic and abiotic stress in agronomic plants.Frontiers in genetics · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are significant class of noncoding RNAs having analytical investigating and modulatory roles in various signaling mechanisms in plants related to growth, development and environmental stress. Conserved miRNAs are an affirmation of land plants evolution and adaptation. They are a proof of indispensable roles of endogenous gene modulators that mediate plant survival on land. Out of such conserved miRNA families, is one core miRNA known as miR166 that is highly conserved among land plants. This particular miRNA is known to primarily target HD ZIP-III transcription factors. miR166 has roles in various developmental processes, as well as regulatory roles against biotic and abiotic stresses in major crop plants. Major developmental roles indirectly modulated by miR166 include shoot apical meristem and vascular differentiation, leaf and root development. In terms of abiotic stress, it has decisive regulatory roles under drought, salinity, and temperature along with biotic stress management. miR166 and its target genes are also known for their beneficial synergy with microorganisms in leguminous crops in relation to lateral roots and nodule development. Hence it is important to study the roles of miR166 in different crop plants to understand its defensive roles against environmental stresses and improve plant productivity by reprogramming several gene functions at molecular levels. This review is hence a summary of different regulatory roles of miR166 with its target HD-ZIP III and its modulatory and fine tuning against different environmental stresses in various plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.