Evidence map›Paper›PMID 34924433›Full record

ArticleJournal of X-ray science and technology2022

Evaluation of an artificial intelligence (AI) system to detect tuberculosis on chest X-ray at a pilot active screening project in Guangdong, China in 2019.

Qinghua Liao, Huiying Feng, Yuan Li, Xiaoyu Lai, Junping Pan, Fangjing Zhou, Lin Zhou, Liang Chen

Open access · hybridAbstract read
In one paragraph

Article in Journal of X-ray science and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qinghua LiaoCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Huiying FengCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Yuan LiScientific and Technological Project Manager, Beijing Capital Technological Project Management Co., Ltd, Beijing, China.
Xiaoyu LaiCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Junping PanCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Fangjing ZhouCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Lin ZhouCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Liang ChenCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Center for Tuberculosis Control of Guangdong Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough computer-aided detection (CAD) software employed with Artificial Intelligence (AI) system has been developed aiming to assist tuberculosis (TB) triage, screening, and diagnosis, its clinical performance for tuberculosis screening remains unknown.

objectiveTo evaluate performance of an CAD software for detecting TB on chest X-ray images at a pilot active TB screening project.

methodsA CAD software scheme employed with AI was used to screen chest X-ray images of participants and produce probability scores of cases being positive for TB. CAD-generated TB detection scores were compared with on-site and senior radiologists via several performance evaluation indices including area under the ROC curves (AUC), specificity, sensitive, and positive predict value. Pycharm CE and SPSS statistics software packages were used for data analysis.

resultsAmong 2,543 participants, eight TB patients were identified from this screening pilot program. The AI-based CAD system outperformed the onsite (AUC = 0.740) and senior radiologists (AUC = 0.805) either using thresholds of 30% (AUC = 0.978) and 50% (AUC = 0.859) when taking the final diagnosis as the ground truth.

conclusionsThe AI-based CAD software successfully detects all TB patients as identified from this study at a threshold of 30%. It demonstrates feasibility and easy accessibility to carry out large scale TB screening using this CAD software equipped in medical vans with chest X-ray imaging machine.

Indexed as

TuberculosisTuberculosis, PulmonaryArtificial IntelligenceHumansPilot ProjectsX-Raysactive TB case screeningartificial intelligencechest X-raycomputer-aided detectionTuberculosis (TB)

Identifiers

PMID34924433
PMCPMC9028657
OpenAlexW4200338444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.