ReviewJournal of obesity & metabolic syndrome2021
Severe Obesity in Children and Adolescents: Metabolic Effects, Assessment, and Treatment.
Review in Journal of obesity & metabolic syndrome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- GLP-1 receptor agonists for the treatment of obesity in children and adolescents: a meta-analysis of randomized controlled trials.Pediatric research · 2026Pooled it
- Body Composition Changes in Adolescents Who Underwent Bariatric Surgery: A Systematic Review and Meta-analysis.Current obesity reports · 2024Pooled it
- Cardiometabolic outcome of MyBFF@school intervention program among secondary schoolchildren: a cluster randomized controlled trial.BMC public health · 2026Trial
- The Role of Parenting in Mitigating Epigenetic Cardiometabolic Risk in a Sample of Predominantly Latino Preschoolers.medRxiv : the preprint server for health sciences · 2026Article
- Bariatric Surgery in Adolescents With Obesity: Weight and Cardiometabolic Outcomes-Real-World Data.Obesity (Silver Spring, Md.) · 2026Article
- Mechanistic study of FA-PG3 nanoparticles promoting adipose browning through the PPARγ and PRDM16-UCP1 pathway in severe pediatric obesity.NPJ science of food · 2026Article
- Anthropometric trajectories of Korean children and adolescents with severe obesity.Clinical and experimental pediatrics · 2026Article
- Assessment of BMI percentages of obesity thresholds and cardiometabolic risk factors in children and adolescents: a retrospective cross-sectional study in Beijing.Lipids in health and disease · 2026Article
- Adherence to Health Behavior Recommendations among Youth with Obesity Classes I, II, and III.Childhood obesity (Print) · 2026Article
- Effectiveness of Bariatric Surgery Versus Nutritional Interventions in Adolescents: A Retrospective Cohort Study.Obesity surgery · 2026Article
- Two Sides of a Coin: Molecular, metabolic, and Phenotypic Convergence in Pediatric Undernutrition and Obesity.Current obesity reports · 2026Review
- The Natural History of Prediabetes and Cardiovascular Disease in the Pediatric Population.Biomedicines · 2026Review
- Effect and safety of a physical exercise-based intervention on body composition and cardiometabolic health of adolescents with severe obesity. Secondary analysis from the PAC-MAnO trial.Obesity pillars · 2025Article
- The stronger predictive role of early life exposures versus current lifestyle behaviors on the development of childhood severe obesity and metabolic dysfunction.BMC pediatrics · 2025Article
- Assessing Appetite-Validation of a Picture-Based Appetite Assessment Tool for Children Aged 6-9 Years-A Pilot Study.Nutrients · 2025Article
- Trends in the Prevalence of Overweight, Obesity and Severe Obesity in Primary School Children in Croatia from 2003 to 2022.Children (Basel, Switzerland) · 2025Article
- Pediatric endoscopic ultrasound-guided liver biopsy: 3-year experience.Journal of pediatric gastroenterology and nutrition · 2025Article
- Effect of the Intervention Dominated by Rational-Emotive Therapy on Obese Children's Mental Health.Iranian journal of public health · 2025Article
- Monogenic etiologies in a cohort of early onset obesity: a real-world experience from Belgium.Frontiers in endocrinology · 2025Article
- Endocrine consequences of childhood obesity: a narrative review.Frontiers in endocrinology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood obesity has been increasing steadily in recent decades, and severe childhood obesity has emerged as a major public health problem both nationally and internationally. A current concern is that lockdown due to the coronavirus disease 2019 (COVID-19) pandemic could exacerbate the spread of childhood obesity and increase the gap in obesity risk. Recent research results indicate the aggravation of obesity after school closures. The consequences of severe childhood obesity are more devastating than those of mild to moderate obesity. Children with severe obesity are at greater risk than others for hypertension, type 2 diabetes, metabolic syndrome, non-alcoholic fatty liver disease, atherosclerosis, and adult obesity. Accurately assessing and diagnosing a child with severe obesity is the key to implementing successful therapy. A detailed and accurate patient history and physical examination are important to discriminate monogenic obesity and metabolic syndrome diagnoses from severe obesity without an underlying cause. Psychosocial factors, including eating behaviors, should be assessed to facilitate better weight management outcomes. Treatment options for severe pediatric obesity include lifestyle modification therapy, pharmacotherapy, and metabolic and bariatric surgery. However, lifestyle modification should be the priority. Although progress has been made, safe and effective treatment for severe pediatric obesity is still challenging. More efforts and innovations are needed to find a solution for the huge medical and emotional burden that these children and their families carry. Public health organizations also need to make efforts to encourage and normalize healthy eating habits and exercise to prevent severe obesity in childhood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.