Evidence map›Paper›PMID 34924275›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2022

Improvements in Cognitive Performance With Computerized Training in Older People With and Without Cognitive Impairment: Synergistic Effects of Skills-Focused and Cognitive-Focused Strategies.

Philip D Harvey, Matthew Zayas-Bazan, Lize Tibiriçá, Peter Kallestrup, Sara J Czaja

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06601933 (Cognitive Training and Neuroplasticity in Mild Cognitive Impairment), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06601933 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

TypeinterventionalSponsorColumbia UniversityRan2024 to 2030Enrolled240ConditionsMild Cognitive Impairment (MCI), Cognitive TrainingArmsCognitive Training
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip D HarveyDepartment of Psychiatry and Behavioral Sciences (PDH), University of Miami, Miami, FL; Research Service Bruce W. Carter VA Medical Center (PDH), Miami, FL; iFunction, Inc., (PDH, MZB, LT, PK, SJC) Miami, FL. Electronic address: philipdharvey1@cs.com.
Matthew Zayas-BazaniFunction, Inc., (PDH, MZB, LT, PK, SJC) Miami, FL.
Lize TibiriçáiFunction, Inc., (PDH, MZB, LT, PK, SJC) Miami, FL; UCSD Medical Center (LT), La Jolla, CA.
Peter KallestrupiFunction, Inc., (PDH, MZB, LT, PK, SJC) Miami, FL.
Sara J CzajaiFunction, Inc., (PDH, MZB, LT, PK, SJC) Miami, FL; Weil Cornell Medicine (SJC), New York, NY.

Funding

A Technology-Based Novel Functional Skills Assessment and Training Program for Adults with and without Cognitive Impairments. Develop the next generation software solution.R44AG057238 · NIA · I-FUNCTION, INC. · PI KALLESTRUP, PETER · 2020 to 2021
$1.6M
A novel computer-based functional skills assessment and training programR43AG057238 · NIA · I-FUNCTION, INC. · PI CZAJA, SARA J, HARVEY, PHILIP D. · 2017 to 2018
$450k
Improving the Functional Outcomes in Older Adults with SchizophreniaR21AG041740 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CZAJA, SARA J, HARVEY, PHILIP D. · 2012 to 2013
$412k
NIA NIH HHS R21 AG041740NIA NIH HHS R43 AG057238NIA NIH HHS R44 AG057238
6 · The paper itself

Abstract

objectivesBoth cognitively impaired (CI) and nonimpaired (NC) older people have challenges in performing everyday tasks. Previous skills training efforts in NC individuals have led to improvements in both functional skills and cognitive functioning. We evaluated the cognitive benefits of combining computerized cognitive training (CCT) with a computer-based functional skills assessment and training (CFSAT) program in a sample of CI and NC older adults.

designRandomized parallel clinical trial with two treatment conditions: up to 24 sessions of CFSAT training alone or CFSAT plus speed focused CCT.

participantsNC (n = 62) and CI (n = 55) older adults, ranging in age from 60-86 years (M = 73.12), primarily female (90%), and ethnically diverse (21% Hispanic, 52% African American). Participants were divided based on Montreal Cognitive Assessment scores and cognitive complaints.

settingThree different community centers in Miami, FL. MEASUREMENTS: The Brief Assessment of Cognition, app version, was used to measure cognitive performance across six different cognitive domains before and after training.

resultsAll six cognitive domains improved from baseline. Multivariate analyses found the effects of the combined CFSAT and CCT to be superior. The interaction of training condition and cognitive status was not statistically significant, indicating no global impact of cognitive status on improvements in cognition across training conditions.

conclusionsCFSAT training was associated with cognitive benefits, particularly in CI participants. The combined intervention led to greater improvements. Consistent with results of previous studies, there is considerable evidence of cognitive plasticity in older adults, including those with CI.

Indexed as

Cognition DisordersCognitive DysfunctionAgedAged, 80 and overCognitionFemaleHumansage-related cognitive changesComputerized cognitive trainingeveryday functional skillsfunctional skills trainingmild cognitive impairment

Identifiers

PMID34924275
PMCPMC9261111

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.