Evidence map›Paper›PMID 34923905›Full record

ArticleGut microbes

Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients.

Camille Amadieu, Valentin Coste, Audrey M Neyrinck, Victoria Thijssen, Quentin Leyrolle, Laure B Bindels, Hubert Piessevaux, Peter Stärkel, Philippe de Timary, Nathalie M Delzenne and 1 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Camille AmadieuMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.
Valentin CosteMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.
Audrey M NeyrinckMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.ORCID 0000-0002-9435-3338
Victoria ThijssenMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.
Quentin LeyrolleMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.
Laure B BindelsMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.ORCID 0000-0003-3747-3234
Hubert PiessevauxDepartment of Hepato-Gastroenterology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Peter StärkelDepartment of Hepato-Gastroenterology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Philippe de TimaryInstitute of Neuroscience, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.ORCID 0000-0003-3956-6848
Nathalie M DelzenneMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.ORCID 0000-0003-2115-6082
Sophie LeclercqMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique De Louvain, UCLouvain, Brussels, Belgium.ORCID 0000-0002-2894-5220
UCLouvain · BECliniques Universitaires Saint-Luc · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) is a chronic relapsing disease associated with malnutrition, metabolic disturbances, and gut microbiota alterations that are correlated with the severity of psychological symptoms. This study aims at supplementing AUD patients with prebiotic fiber during alcohol withdrawal, in order to modulate the gut microbiota composition and to evaluate its effect on gastrointestinal tolerance, metabolism, and patient's behavior. A randomized, double-blind, placebo-controlled study included 50 AUD patients assigned to inulin

Indexed as

Gastrointestinal MicrobiomeAdolescentAdultAgedAlcoholismBacteriaDietary FiberDouble-Blind MethodFecesFemaleGastrointestinal TractHumansInulinMaleMiddle AgedPilot ProjectsDietary FiberInulinPrebioticsalcohol use disorderGut-brain axisinulinprebioticspsychological symptomssociability

Identifiers

PMID34923905
PMCPMC8726664
OpenAlexW4200524215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.