Evidence map›Paper›PMID 34923888›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Flavonoids as tyrosinase inhibitors in

Katarzyna Jakimiuk, Suat Sari, Robert Milewski, Claudiu T Supuran, Didem Şöhretoğlu, Michał Tomczyk

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Advancing the Potential ofPlants (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Review
  6. Bioactive Potential ofPlants (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Assessment of the Antioxidant and Photoprotective Properties ofInternational journal of molecular sciences · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Flavonoids fromADMET & DMPK · 2024
    Review
  15. Article
  16. Oxidation of flavonoids by tyrosinase and byJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  17. Review
  18. Microorganisms · 2023
    Article
  19. Chemical Characterization of Different Extracts ofAntioxidants (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 5 countries.

Katarzyna JakimiukDepartment of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Białystok, Poland.ORCID 0000-0001-7702-6493
Suat SariDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-8248-4218
Robert MilewskiDepartment of Statistics and Medical Informatics, Faculty of Health Science, Medical University of Białystok, Białystok, Poland.ORCID 0000-0001-6241-8283
Claudiu T SupuranNeurofarba Department, Universita degli Studi di Firenze, Florence, Italy.ORCID 0000-0003-4262-0323
Didem ŞöhretoğluDepartment of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-8264-5544
Michał TomczykDepartment of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Białystok, Poland.ORCID 0000-0002-4063-1048
Medical University of Białystok · PLHacettepe University · TRUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids are widely distributed in plants and constitute the most common polyphenolic phytoconstituents in the human diet. In this study, the

Indexed as

AgaricalesDose-Response Relationship, DrugEnzyme InhibitorsFlavonoidsHumansModels, MolecularMolecular StructureMonophenol MonooxygenaseStructure-Activity RelationshipEnzyme InhibitorsFlavonoidsMonophenol MonooxygenaseFlavonoidmolecular dockingstatistical analysisstructure-activity relationshiptyrosinase

Identifiers

PMID34923888
PMCPMC8735877
OpenAlexW4200109553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.