Evidence map›Paper›PMID 34923849›Full record

ArticleBone & joint research2021

3D printing in orthopaedic surgery: a scoping review of randomized controlled trials.

Ronald Man Yeung Wong, Pui Yan Wong, Chaoran Liu, Yik Lok Chung, Kwok Chuen Wong, Chi Yin Tso, Simon Kwoon-Ho Chow, Wing-Hoi Cheung, Patrick Shu-Hang Yung, Chun Sing Chui and 1 more

Abstract readScoping Review
In one paragraph

Article in Bone & joint research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Review
  5. Three-Dimensional Printing in Pediatric Orthopaedics: Cost Analysis and Emerging Applications.Journal of the Pediatric Orthopaedic Society of North America · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Bioprinting for craniofacial reconstruction: A review of advancements, clinical use, and challenges.Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · 2025
    Review
  14. Review
  15. Article
  16. Applications of 3D printing in orthopedics: a scoping review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ronald Man Yeung WongDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0001-5615-6627
Pui Yan WongDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0001-6513-1843
Chaoran LiuDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0001-9620-8794
Yik Lok ChungDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0002-5382-2759
Kwok Chuen WongDepartment of Orthopaedics & Traumatology, Prince of Wales Hospital, Hong Kong, Hong Kong.ORCID 0000-0002-2960-3003
Chi Yin TsoDepartment of Orthopaedics & Traumatology, Prince of Wales Hospital, Hong Kong, Hong Kong.ORCID 0000-0001-9848-7790
Simon Kwoon-Ho ChowDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0003-1742-980X
Wing-Hoi CheungDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0003-3247-8255
Patrick Shu-Hang YungDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0002-7214-5503
Chun Sing ChuiDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0003-4195-6773
Sheung Wai LawDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0001-7923-0164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe use of 3D printing has become increasingly popular and has been widely used in orthopaedic surgery. There has been a trend towards an increasing number of publications in this field, but existing literature incorporates limited high-quality studies, and there is a lack of reports on outcomes. The aim of this study was to perform a scoping review with Level I evidence on the application and effectiveness of 3D printing.

methodsA literature search was performed in PubMed, Embase, and Web of Science databases. The keywords used for the search criteria were ((3d print*) OR (rapid prototyp*) OR (additive manufactur*)) AND (orthopaedic). The inclusion criteria were: 1) use of 3D printing in orthopaedics, 2) randomized controlled trials, and 3) studies with participants/patients. Risk of bias was assessed with Cochrane Collaboration Tool and PEDro Score. Pooled analysis was performed.

resultsOverall, 21 studies were included in our study with a pooled total of 932 participants. Pooled analysis showed that operating time (p < 0.001), blood loss (p < 0.001), fluoroscopy times (p < 0.001), bone union time (p < 0.001), pain (p = 0.040), accuracy (p < 0.001), and functional scores (p < 0.001) were significantly improved with 3D printing compared to the control group. There were no significant differences in complications.

conclusion3D printing is a rapidly developing field in orthopaedics. Our findings show that 3D printing is advantageous in terms of operating time, blood loss, fluoroscopy times, bone union time, pain, accuracy, and function. The use of 3D printing did not increase the risk of complications. Cite this article:

Indexed as

3D printingblood lossbone unionfluoroscopyFunctional outcomefunctional scoreslower limb surgeriesMeta-analysisorthopaedic surgeriesOrthopaedic surgerypain scorerandomized controlled trialsRandomized controlled trialsspine surgeriesupper limb surgeries

Identifiers

PMID34923849
PMCPMC8696518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.