Evidence map›Paper›PMID 34923745›Full record

ArticleThe FEBS journal2022

Role of geochemical protoenzymes (geozymes) in primordial metabolism: specific abiotic hydride transfer by metals to the biological redox cofactor NAD

Delfina P Henriques Pereira, Jana Leethaus, Tugce Beyazay, Andrey do Nascimento Vieira, Karl Kleinermanns, Harun Tüysüz, William F Martin, Martina Preiner

Open access · hybridAbstract read
In one paragraph

Article in The FEBS journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

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  13. Chemical Antiquity in Metabolism.Accounts of chemical research · 2024
    Article
  14. Ferredoxin reduction by hydrogen with iron functions as an evolutionary precursor of flavin-based electron bifurcation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Electron transport chains as a window into the earliest stages of evolution.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Delfina P Henriques PereiraInstitute for Molecular Evolution, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0001-6131-1740
Jana LeethausInstitute for Molecular Evolution, Heinrich Heine University, Düsseldorf, Germany.
Tugce BeyazayMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.ORCID 0000-0001-5162-8541
Andrey do Nascimento VieiraInstitute for Molecular Evolution, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0003-4468-7724
Karl KleinermannsInstitute for Physical Chemistry, Heinrich Heine University, Düsseldorf, Germany.
Harun TüysüzMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.ORCID 0000-0001-8552-7028
William F MartinInstitute for Molecular Evolution, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0003-1478-6449
Martina PreinerDepartment of Ocean Systems, Royal Netherlands Institute for Sea Research, Den Burg, The Netherlands.ORCID 0000-0001-5137-5556
Heinrich Heine University Düsseldorf · DEMax-Planck-Institut für Kohlenforschung · DEUniversity of Applied Sciences Utrecht · NL

Funding

European Research Council 101018894
6 · The paper itself

Abstract

Hydrogen gas, H

Indexed as

HydrogenaseNADHydrogenIronMetalsNickelOxidation-ReductionWaterHydrogenHydrogenaseIronMetalsNADNickelWatercofactorselectron donorshydrogenhydrogenaseNADHorigin of lifereductionserpentinizing systems

Identifiers

PMID34923745
PMCPMC9306933
OpenAlexW4200345879

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.