Evidence map›Paper›PMID 34923484›Full record

ArticleAging2021

Structural, functional and molecular pathogenesis of pelvic organ prolapse in patient and

Yu Li, Nanfang Nie, Lin Gong, Fangyuan Bao, Chengrui An, Hongxia Cai, Xudong Yao, Yanshan Liu, Chunbo Yang, Bingbing Wu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Inflammatory Cells in Control and Prolapsed Uterosacral Ligament Tissue.Reproductive sciences (Thousand Oaks, Calif.) · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Balkan medical journal · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Current practice in animal models for pelvic floor dysfunction.International urogynecology journal · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yu LiClinical Research Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Nanfang NieClinical Research Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Lin GongClinical Research Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Fangyuan BaoDr. Li Dak Sum and Yip Yio Chin Center for Stem Cells and Regenerative Medicine, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Chengrui AnDr. Li Dak Sum and Yip Yio Chin Center for Stem Cells and Regenerative Medicine, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Hongxia CaiClinical Research Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Xudong YaoDr. Li Dak Sum and Yip Yio Chin Center for Stem Cells and Regenerative Medicine, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Yanshan LiuClinical Research Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Chunbo YangDepartment of Gynaecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Bingbing WuDr. Li Dak Sum and Yip Yio Chin Center for Stem Cells and Regenerative Medicine, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
XiaoHui ZouClinical Research Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China.
Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CNWomen's Hospital, School of Medicine, Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pelvic organ prolapse is a worldwide health problem to elderly women. Understanding its pathogenesis and an ideal animal model are crucial to developing promising treatments. The present study aimed to investigate new clinical significance and detailed mechanism of pelvic organ prolapse by comparing the structural, functional and molecular dysfunctions of pelvic organ prolapse in patient and

Indexed as

Gene OntologyPelvic Organ ProlapseAgedAged, 80 and overAmino Acid OxidoreductasesAnimalsCollagenDisease Models, AnimalFemaleHumansMiceMice, Inbred C57BLMice, KnockoutMiddle AgedAmino Acid OxidoreductasesCollagenLoxl1 protein, mouseanimal modelLoxl1 knockout micepathogenesispelvic organ prolapse

Identifiers

PMID34923484
PMCPMC8751609
OpenAlexW4200183631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.