Evidence map›Paper›PMID 34923358›Full record

ArticleJournal of psychiatric research2022

Assessment of improvement in anxiety severity for children with autism spectrum disorder: The matched correspondence analysis approach.

Se-Kang Kim, Dean McKay, Sandra L Cepeda, Sophie C Schneider, Jeffrey Wood, Eric A Storch

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Se-Kang KimDepartment of Psychology, Fordham University, USA. Electronic address: sekim@fordham.edu.
Dean McKayDepartment of Psychology, Fordham University, USA.
Sandra L CepedaDepartment of Psychiatry & Behavioral Sciences, Baylor College of Medicine, USA.
Sophie C SchneiderDepartment of Psychiatry & Behavioral Sciences, Baylor College of Medicine, USA.
Jeffrey WoodDepartment of Education, University of California, Los Angeles, USA.
Eric A StorchDepartment of Psychiatry & Behavioral Sciences, Baylor College of Medicine, USA.
Baylor College of Medicine · USFordham University · USUniversity of California, Los Angeles · US

Funding

Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Sandesh Chakravarthy Sreenath Nagamani, David Loren Nelson · 2020 to 2026
$9.9M
NICHD NIH HHS P50 HD103555
6 · The paper itself

Abstract

introductionClinical trials typically involve random assignment to treatment conditions. However, random assignment does not guarantee a lack of systematic variation in the outcomes, and application of covariation methods for multiple dependent measures requires complicated assumptions that are often not met.

methodsThis study employed matched correspondence analysis (CA) for controlling systematic variation and handling multiple outcomes. One hundred nine children with autism spectrum disorder (ASD) were assessed for anxiety symptom severity across four studies, where participants were randomly assigned to either cognitive behavioral therapy (CBT) or treatment as usual or waitlist (TAU/WT). Matched CA is designed to optimally scale only the differences between baseline and posttreatment, rendering the systematic baseline carryover effects irrelevant.

resultsDifferences in treatment efficacy were observed. CBT showed treatment efficacy on anxiety severity and anxiety-related impairment relative to TAU/WT, after the control of baseline carryover effects.

conclusionThis study provides a way to control systematic variation between groups at the outset of treatment trials and is expected to provide a novel pathway to more proper assessment of treatment efficacy for children with ASD and anxiety.

Indexed as

Autism spectrum disorder (ASD)Cognitive behavioral therapy (CBT)Matched correspondence analysisTreatment as usual (TAU)

Identifiers

PMID34923358
PMCPMC9198104
OpenAlexW4200405868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.